drugset / Trial / NCT04988555

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

NCT04988555

Phase 1/2 Recruiting 606 enrolled Sumitomo Pharma America, Inc.
Non-randomizedParallel-groupOpen-labelTreatment

Summary

A phase 1/2 dose escalation / dose expansion study of Enzomenib (DSP-5336) in patients with acute leukemia.

Timeline

Start
2022-02-28
Primary completion
2027-06-30
Completion
2027-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Enzomenib Small molecule Oral
Background Azacitidine Other / unclassified Oral
Background Cytarabine Small molecule
Background Daunorubicin Small molecule
Background Fluconazole Small molecule
Background Gilteritinib Small molecule Oral
Background Posaconazole Small molecule
Background Venetoclax Small molecule Oral
Background Voriconazole Small molecule