Drugs / Levorphanol
Levorphanol
also known as
Aromarone · IDS-NL-007 · Levo-dromoran · Levorfanol · Levorphan · LEVORPHANOL HYDROCHLORIDE · LEVORPHANOL TARTRATE · Levorphanol tartrate anhydrous · +4 more
Small molecule targets OPRM1 via activation
Regulatory milestones approvals, filings & regulatory actions · 2 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | LEVO-DROMORAN | — | 1991-12-19 | fda.gov ↗ |
| Approved | US (FDA) | LEVO-DROMORAN | — | 1953-01-08 | fda.gov ↗ |
Trials 2 · a red edge is where a trial was stopped
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT03579446 | Nov 2018 → Jun 2023 | hematopoietic and lymphoid cell neoplasm, metastatic malignant neoplasm | M.D. Anderson Cancer Center | Terminated | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT00275249 | Mar 2001 → Oct 2004 | chronic pain syndrome | University of California, San Francisco | Completed | No outcome recorded |
Evidence & citations 17 cited values
Every value below carries the sentence it was read from. 3 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | levorphanol | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00275249 ↗ |
| Known as | Aromarone | ChEMBL registry synonym — accepted as the source's own label CHEMBL592 ↗ |
| Known as | IDS-NL-007 | ChEMBL registry synonym — accepted as the source's own label CHEMBL592 ↗ |
| Known as | Levo-dromoran | ChEMBL registry synonym — accepted as the source's own label CHEMBL592 ↗ |
| Known as | Levorfanol | ChEMBL registry synonym — accepted as the source's own label CHEMBL592 ↗ |
| Known as | Levorphan | ChEMBL registry synonym — accepted as the source's own label CHEMBL592 ↗ |
| Known as | LEVORPHANOL HYDROCHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL592 ↗ |
| Known as | LEVORPHANOL TARTRATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL592 ↗ |
| Known as | Levorphanol tartrate anhydrous | ChEMBL registry synonym — accepted as the source's own label CHEMBL592 ↗ |
| Known as | Levorphanol tartrate dihydrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL592 ↗ |
| Known as | NSC-91012 | ChEMBL registry synonym — accepted as the source's own label CHEMBL592 ↗ |
| Known as | RO 1-5431 | ChEMBL registry synonym — accepted as the source's own label CHEMBL592 ↗ |
| Known as | RO-1-5431/7 | ChEMBL registry synonym — accepted as the source's own label CHEMBL592 ↗ |
| Action | Activate | “Mu opioid receptor agonist” CHEMBL592 ↗ |
| Modality | Small molecule | — CHEMBL592 ↗ |
| Route | Oral | “Given PO” NCT03579446 ↗ |
| Target | OPRM1 | “Mu opioid receptor agonist” CHEMBL592 ↗ |