Drugs / CPP-ACP

Trials 7 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 22 trials
Phase 2 NCT03865680 Apr 2019 → Mar 2020 Nourhan M.Aly Completed No outcome recorded
Phase 2 NCT01737307 Mar → Jun 2011 infectious disease, mucositis Azad University of Medical Sciences Completed No outcome recorded
Phase 42 trials
Phase 4 NCT03426150 Dec 2015 → Oct 2017 tooth erosion, non-bacterial Fujian Medical University Completed No outcome recorded
Phase 4 NCT02424097 May 2013 → Oct 2016 smooth surface dental caries University of California, San Francisco Completed No outcome recorded
Phase not applicable3 trials
NCT06463938 May → Aug 2024 overdue cervix disorder, dentin sensitivity, hypersensitivity reaction disease Dow University of Health Sciences Recruiting No outcome recorded
NCT04788550 Mar 2021 → Sep 2022 malposition of teeth with or without hypodontia/oligodontia University of Malaya Unknown No outcome recorded
NCT04112706 Jul 2006 → Feb 2007 dentin sensitivity University of New England Completed No outcome recorded
Also used as a comparator or background therapy in 7 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT05202821 Comparator Jan 2021 → Mar 2022 smooth surface dental caries Ain Shams University Unknown No outcome recorded
Phase 23 trials
Phase 2 NCT03973554 Comparator Oct 2019 → Oct 2020 smooth surface dental caries Ruba Alaa El Din Adel El Damarisy Unknown No outcome recorded
Phase 2 NCT03976583 Comparator Sep 2019 → Sep 2020 Cairo University Unknown No outcome recorded
Phase 2 NCT01604109 Comparator Jul 2010 → Sep 2011 dental caries Thammasat University Completed No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT04422860 Comparator Oct 2020 → Sep 2021 dental caries Cairo University Unknown No outcome recorded
Phase 31 trial
Phase 3 NCT04401280 Comparator Jun 2020 → Jun 2021 smooth surface dental caries Rania Salah Completed No outcome recorded
Phase not applicable1 trial
NCT01566357 Comparator Jan 2012 → May 2013 University of Zurich Completed No outcome recorded

Evidence & citations 8 cited values

Every value below carries the sentence it was read from. 17 sources stand behind the page.

FieldValueCited text
Known as CPP-ACP “This research aims to determine the effectiveness of Casein phosphopeptide amorphous calcium phosphate paste (CPP-ACP) used alone or combined with a diode laser in treating...” PMID 41789288 Dec 2025
11

“10% w/v CPP-ACP, 5% sodium fluoride varnish” NCT04422860

NCT04112706

NCT03426150

NCT03973554

NCT01604109

NCT01737307

NCT02424097

NCT04788550

NCT03865680

NCT04401280

NCT03976583

Known as Calcium Phosphopeptide Amorphous Calcium Phosphate “This clinical trial tested the effect of daily application of 10% w/v calcium phosphopeptide-amorphous calcium phosphate (CPP-ACP) paste for 1 yr when added to regular...” PMID 22805294 Jul 2012
Known as Casein phospho peptide paste “Therefore, this research aims to determine the effectiveness of Casein phospho peptide paste (CPP-ACP) used alone or combined with a diode laser (LASOTRONIX).” NCT06463938
Known as Casein phosphopeptide amorphous calcium phosphate paste “This research aims to determine the effectiveness of Casein phosphopeptide amorphous calcium phosphate paste (CPP-ACP) used alone or combined with a diode laser in treating...” PMID 41789288 Dec 2025
Known as MI paste ClinicalTrials.gov intervention name — accepted as the source's own label NCT05202821
Known as Tooth Mousse ClinicalTrials.gov intervention name — accepted as the source's own label NCT01566357
Modality Other / unclassified “CPP-ACP paste” PMID 25038509 Jul 2014
Route Topical “home application after brushing in the evening” NCT02424097