Drugs / Edasalonexent
last change Oct 2020 re-read 2 minutes ago

Edasalonexent

also known as CAT-1004 · Edasalonexento

Small molecule

Developed for
Duchenne muscular dystrophy · type 2 diabetes mellitus
Investigated by
Catabasis Pharmaceuticals

Trials 7 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT04543370 Aug → Sep 2020 Catabasis Pharmaceuticals Completed No outcome recorded
Phase 1 NCT01670773 Aug → Oct 2012 Catabasis Pharmaceuticals Completed No outcome recorded
Phase 1 NCT01511900 Dec 2011 → Apr 2012 type 2 diabetes mellitus Catabasis Pharmaceuticals Completed No outcome recorded
Phase 1 NCT01440166 Sep 2011 → Jan 2012 Catabasis Pharmaceuticals Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT02439216 Apr 2016 → Jan 2017 Duchenne muscular dystrophy Catabasis Pharmaceuticals Completed No outcome recorded
Phase 32 trials
Phase 3 NCT03917719 Mar 2019 → Oct 2020 Duchenne muscular dystrophy Catabasis Pharmaceuticals Terminated No outcome recorded
Phase 3 NCT03703882 Oct 2018 → Sep 2020 Duchenne muscular dystrophy Catabasis Pharmaceuticals Completed No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 8 sources stand behind the page.

FieldValueCited text
Known as Edasalonexent ClinicalTrials.gov intervention name — accepted as the source's own label NCT04543370
3

NCT02439216

NCT03703882

NCT03917719

Known as CAT-1004 “Multiple dose oral administration once daily for 14 days of CAT 1004 at dose level 1-9 subjects will be treated with CAT-1004NCT01511900
5

“Single dose oral administration of CAT1004 or placebo-6 to 8 subjects will be treated with CAT-1004 per cohort.” NCT01440166

“Single dose oral administration of CAT1004 or placebo-6 to 8 subjects will be treated with CAT-1004 per cohort.” NCT01440166

CAT-1004NCT03703882

NCT01511900

NCT01670773

Known as Edasalonexento ChEMBL registry synonym — accepted as the source's own label CHEMBL3786673
Action Inhibit “targeted to inhibit activated NF-κB” NCT02439216
Modality Small molecule “Edasalonexent is an orally administered small moleculeNCT02439216
Route Oral “Single dose oral administration” NCT01440166