Drugs / IPH5201
last change Apr 2026 re-read 9 days ago

IPH5201

Developed for
neoplasm · non-small cell lung carcinoma
Investigated by
Innate Pharma · MedImmune LLC

Trials 2

20202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT04261075 Mar 2020 → Jun 2022 neoplasm MedImmune LLC Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05742607 Jun 2023 → Jun 2027 expected non-small cell lung carcinoma Innate Pharma Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 4

DateIssuerRelease
2026-04-17 Innate Pharma Results Innate Pharma to present MATISSE Phase 2 interim results of IPH5201 in Clinical Trials Plenary Session at AACR 2026 innate-pharma.com ↗
The combination of IPH5201 with durvalumab and chemotherapy demonstrated higher pathological complete response (pCR) rates compared with the benchmark set by durvalumab plus chemotherapy alone.
2019-11-06 Innate Pharma Results Innate Pharma announces preclinical data presentations at SITC 2019 innate-pharma.com ↗
In vivo data on anti-CD39 IPH5201 supporting the rationale for assessing combination with PD-1/PD-L1 checkpoint inhibitors
2019-05-23 Innate Pharma Results Innate Pharma announces publication on next generation immunotherapies targeting the adenosine pathway in “Cell Reports” innate-pharma.com ↗
In vitro and in vivo data support the use of anti-CD39 and anti-CD73 mAbs in combination cancer therapies.
2019-04-01 Innate Pharma Results Innate Pharma highlights next generation of cancer immunotherapies at the American Association of Cancer Research (AACR) 2019 annual meeting innate-pharma.com ↗
New preclinical data highlights IPH5201 (anti-CD39) and IHP5301 (anti-CD73) neutralizing antibodies targeting the immunosuppressive adenosine pathway

Evidence & citations 1 cited value

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as IPH5201 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05742607 ↗
1

NCT04261075 ↗