Drugs / Nanohydroxyapatite

Trials 9

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT06493500 Jul 2024 → Feb 2025 overdue dentin sensitivity Cairo University Not yet recruiting No outcome recorded
Phase 1 NCT05771077 Jun → Dec 2022 — Egymedicalpedia Completed No outcome recorded
Phase 21 trial
Phase 2 NCT02918617 May 2015 → Sep 2016 dentin sensitivity The University of Texas Health Science Center at San Antonio Completed No outcome recorded
Phase 41 trial
Phase 4 NCT04887389 Aug 2021 → Sep 2022 dental caries Nisreen Ibrahim khan Completed No outcome recorded
Phase not applicable5 trials
— NCT07056855 Jul 2025 overdue dentin sensitivity Cairo University Not yet recruiting No outcome recorded
— NCT07608783 Jul 2025 → Aug 2026 overdue periodontitis Cairo University Active not recruiting No outcome recorded
— NCT06896565 Jun → Aug 2025 overdue — Cairo University Not yet recruiting No outcome recorded
— NCT06834464 Dec 2024 → Jan 2025 — National Research Centre, Egypt Completed No outcome recorded
— NCT06821724 Dec 2024 → Jan 2025 smooth surface dental caries National Research Centre, Egypt Completed No outcome recorded
Comparator or background therapy1 trial
Phase 0 NCT02810548 Comparator Feb 2015 → Nov 2016 disease of bone structure King Abdulaziz University Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 12 sources stand behind the page.

FieldValueCited text
Known as Nanohydroxy apatite “To compare the effect of Nanohydroxy apatite (NHA), Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), CPP-ACP with fluoride (CPP-ACPF), versus fluoride gel on...” PMID 40830200 ↗ Aug 2025
10

“nanohydroxyapatite (nano-HAP)-containing toothpastes and cream” NCT02918617 ↗

“Poly Amido Amine Dendrimer, Nanohydroxy apatite” NCT05771077 ↗

NCT06896565 ↗

NCT06821724 ↗

NCT06493500 ↗

NCT07056855 ↗

NCT04887389 ↗

NCT02810548 ↗

NCT06834464 ↗

NCT07608783 ↗

Known as Apagard primo toothpaste “Group 2: Nano hydroxyapatite paste (Apagard primo toothpaste) was applied for 5 minutes.” NCT06834464 ↗
Known as nano-HAP “nanohydroxyapatite (nano-HAP)-containing toothpastes and cream” NCT02918617 ↗
Known as NHA “To compare the effect of Nanohydroxy apatite (NHA), Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), CPP-ACP with fluoride (CPP-ACPF), versus fluoride gel on...” PMID 40830200 ↗ Aug 2025
2

“A single dose of nano-hydroxyapatite (nHA) gel applied subgingivally directly into the periodontal pocket associated with the intrabony defect immediately following debridement” NCT07608783 ↗

“Nanohydroxyapatite (NHA) paste is one of the most recent non-fluoridated remineralizing agents” PMID 41530802 ↗ Jan 2026

Route Topical “patients would be instructed to treat their teeth for 5 min twice a day with the provided toothpaste.” NCT06493500 ↗