Drugs / Poly(Amidoamine) dendrimer
Poly(Amidoamine) dendrimer
Trials 9 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT06493500 | Jul 2024 → Feb 2025 overdue | dentin sensitivity | Cairo University | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT05771077 | Jun → Dec 2022 | — | Egymedicalpedia | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT02918617 | May 2015 → Sep 2016 | dentin sensitivity | The University of Texas Health Science Center at San Antonio | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT04887389 | Aug 2021 → Sep 2022 | dental caries | Nisreen Ibrahim khan | Completed | No outcome recorded |
| Phase not applicable5 trials | ||||||
| — | NCT07056855 | Jul 2025 overdue | dentin sensitivity | Cairo University | Not yet recruiting | No outcome recorded |
| — | NCT07608783 | Jul 2025 → Aug 2026 overdue | periodontitis | Cairo University | Active not recruiting | No outcome recorded |
| — | NCT06896565 | Jun → Aug 2025 overdue | — | Cairo University | Not yet recruiting | No outcome recorded |
| — | NCT06834464 | Dec 2024 → Jan 2025 | — | National Research Centre, Egypt | Completed | No outcome recorded |
| — | NCT06821724 | Dec 2024 → Jan 2025 | smooth surface dental caries | National Research Centre, Egypt | Completed | No outcome recorded |
Also used as a comparator or background therapy in 2 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT02810548 Comparator | Feb 2015 → Nov 2016 | disease of bone structure | King Abdulaziz University | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT06662604 Comparator | Oct 2024 → Sep 2025 overdue | cysts and fistulae of the face and oral cavity | Cairo University | Not yet recruiting | No outcome recorded |
Evidence & citations 8 cited values
Every value below carries the sentence it was read from. 14 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Poly(Amidoamine) dendrimer | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05771077 ↗ |
| Known as | Apagard primo toothpaste | “Group 2: Nano hydroxyapatite paste (Apagard primo toothpaste) was applied for 5 minutes.” NCT06834464 ↗ |
| Known as | bone graft | ClinicalTrials.gov intervention name — accepted as the source's own label NCT06662604 ↗ |
| Known as | nano-HAP | “nanohydroxyapatite (nano-HAP)-containing toothpastes and cream” NCT02918617 ↗ |
| Known as | Nanohydroxy apatite | “To compare the effect of Nanohydroxy apatite (NHA), Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), CPP-ACP with fluoride (CPP-ACPF), versus fluoride gel on...” PMID 40830200 ↗ Aug 202510“nanohydroxyapatite (nano-HAP)-containing toothpastes and cream” NCT02918617 ↗ “Poly Amido Amine Dendrimer, Nanohydroxy apatite” NCT05771077 ↗ |
| Known as | NHA | “To compare the effect of Nanohydroxy apatite (NHA), Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), CPP-ACP with fluoride (CPP-ACPF), versus fluoride gel on...” PMID 40830200 ↗ Aug 20252“A single dose of nano-hydroxyapatite (nHA) gel applied subgingivally directly into the periodontal pocket associated with the intrabony defect immediately following debridement” NCT07608783 ↗ “Nanohydroxyapatite (NHA) paste is one of the most recent non-fluoridated remineralizing agents” PMID 41530802 ↗ Jan 2026 |
| Modality | Small molecule | — CHEMBL2147156 ↗ |
| Route | Topical | “patients would be instructed to treat their teeth for 5 min twice a day with the provided toothpaste.” NCT06493500 ↗ |