Drugs / RO5093151
last change Jul 2016 re-read 9 days ago

RO5093151

Developed for
glaucoma · NAFLD1 · open-angle glaucoma · type 2 diabetes mellitus
Investigated by
Hoffmann-La Roche

Trials 5

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 13 trials · 1 met primary
Phase 1 NCT02622334 Dec 2015 → Jul 2016 glaucoma Hoffmann-La Roche Completed No outcome recorded
Phase 1 NCT01591850 Sep → Nov 2011 — Hoffmann-La Roche Completed No outcome recorded
Phase 1 NCT01277094 Apr 2011 → Mar 2012 NAFLD1 Hoffmann-La Roche Completed Met primary
Phase 22 trials
Phase 2 NCT01493271 Dec 2011 → Nov 2012 open-angle glaucoma Hoffmann-La Roche Completed No outcome recorded
Phase 2 NCT00823680 Apr → Aug 2009 type 2 diabetes mellitus Hoffmann-La Roche Completed No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as RO5093151 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01277094 ↗
4

NCT01591850 ↗

NCT01493271 ↗

NCT00823680 ↗

NCT02622334 ↗

Action Inhibit “Inhibition of 11β-HSD1 by RO5093151 was effective and safe in reducing liver-fat content” PMID 24795254 ↗ Feb 2014
Route Oral “400mg po bid for 4 weeks” NCT00823680 ↗