drugset / Trial / NCT02622334

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO5093151 in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT).

NCT02622334

Phase 1 Completed 45 enrolled Hoffmann-La Roche
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of the study is to assess the safety, tolerability, and IOP effects of RO5093151 following 7 days of topical ocular treatment in patients with primary open angle glaucoma or ocular hypertension.

Timeline

Start
2015-12-29
Primary completion
2016-07-28
Completion
2016-07-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Latanoprost Small molecule 0.005 % Topical
Subject RO5093151 Unknown 0.1 % Topical
Subject RO5093151 Unknown 0.5 % Topical
Subject RO5093151 Unknown 1 % Topical

Indications