Drugs / Emactuzumab
Trials 7 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 14 trials | ||||||
| Phase 1 | NCT03369964 | Mar → Dec 2018 | non-Hodgkin lymphoma | Hoffmann-La Roche | Withdrawn | No outcome recorded |
| Phase 1 | NCT02760797 | May 2016 → Apr 2018 | neoplasm | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 1 | NCT02323191 | Jan 2015 → Aug 2020 | — | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 1 | NCT01494688 | Dec 2011 → Feb 2018 | cancer | Hoffmann-La Roche | Completed | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT02923739 | May 2017 → Sep 2022 | fallopian tube clear cell adenocarcinoma, fallopian tube endometrioid adenocarcinoma, fallopian tube mucinous adenocarcinoma, fallopian tube serous adenocarcinoma +10 | M.D. Anderson Cancer Center | Terminated | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT05417789 | Oct 2024 → Dec 2025 overdue | giant cell tumor of soft tissue | SynOx Therapeutics Limited | Active not recruiting | No outcome recorded |
| Phase 3 | NCT03768063 | Feb 2019 → Jul 2028 expected | cancer | Hoffmann-La Roche | Active not recruiting | No outcome recorded |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 10 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Emactuzumab | “Emactuzumab (RG7155) is a novel monoclonal antibody that inhibits CSF1R activation.” PMID 26179200 ↗ Jul 2015 |
| Known as | 7i1955n5wx | ChEMBL registry synonym — accepted as the source's own label CHEMBL3545370 ↗ |
| Known as | CXD-301 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3545370 ↗ |
| Known as | RG-7155 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3545370 ↗ |
| Known as | RO-5509554 | ChEMBL registry synonym — accepted as the source's own label CHEMBL3545370 ↗ |
| Known as | RO5509554 (ANTI-CSF-R1) | ChEMBL registry synonym — accepted as the source's own label CHEMBL3545370 ↗ |
| Action | Inhibit | “inhibits CSF1R activation” PMID 26179200 ↗ Jul 2015 |
| Modality | Monoclonal antibody | “a humanised anti-colony stimulating factor 1 receptor (CSF1R) monoclonal antibody” PMID 33161240 ↗ Nov 2020 |
| Route | Intravenous | “Patients received intravenous (IV) emactuzumab” PMID 33161240 ↗ Nov 2020 |
| Target | CSF1R | “Anti-CSF-1R emactuzumab in combination with anti-PD-L1 atezolizumab” PMID 35577503 ↗ May 2022 |