drugset / Trial / NCT03369964
A Study of Atezolizumab in Combination With an Immunotherapy Agent Investigated With or Without Anti-Cd20 Therapy in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma
RandomizedParallel-groupOpen-labelTreatment
Summary
This study will investigate the safety, pharmacology, and activity of atezolizumab in combination with immunotherapy agents with or without an anti-CD20 agent (i.e., obinutuzumab) in patients with relapsed or refractory (R/R) follicular lymphoma (FL). The first immunotherapy molecule investigated will be emactuzumab (Arm A) in two combinations.
Timeline
- Start
- 2018-03-14
- Primary completion
- 2018-12-31
- Completion
- 2019-08-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Atezolizumab | Monoclonal antibody | 1200 mg | Intravenous |
| Subject | Emactuzumab | Monoclonal antibody | 1000 mg | Intravenous |
| Comparator | Obinutuzumab | Monoclonal antibody | 1000 mg | Intravenous |