drugset / Trial / NCT03369964

A Study of Atezolizumab in Combination With an Immunotherapy Agent Investigated With or Without Anti-Cd20 Therapy in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

NCT03369964

Phase 1 Withdrawn Hoffmann-La Roche
RandomizedParallel-groupOpen-labelTreatment

Summary

This study will investigate the safety, pharmacology, and activity of atezolizumab in combination with immunotherapy agents with or without an anti-CD20 agent (i.e., obinutuzumab) in patients with relapsed or refractory (R/R) follicular lymphoma (FL). The first immunotherapy molecule investigated will be emactuzumab (Arm A) in two combinations.

Timeline

Start
2018-03-14
Primary completion
2018-12-31
Completion
2019-08-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Atezolizumab Monoclonal antibody 1200 mg Intravenous
Subject Emactuzumab Monoclonal antibody 1000 mg Intravenous
Comparator Obinutuzumab Monoclonal antibody 1000 mg Intravenous

Indications