Drugs / Atezolizumab
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Atezolizumab

Monoclonal antibody targets CD274 via inhibition

Developed for
non-small cell lung carcinoma · hepatocellular carcinoma · small cell lung carcinoma · cancer · triple-negative breast carcinoma · colorectal cancer · breast cancer · melanoma
+230 more · urothelial carcinoma · urinary bladder cancer · renal cell carcinoma · gastric cancer · cervical cancer · head and neck squamous cell carcinoma · metastatic malignant neoplasm · neoplasm · ovarian cancer · castration-resistant prostate carcinoma · female breast carcinoma · head and neck cancer · esophageal cancer · HER2 positive breast carcinoma · malignant pancreatic neoplasm · cutaneous melanoma · acute myeloid leukemia · cutaneous neuroendocrine carcinoma · diffuse large B-cell lymphoma · endometrial cancer · gastroesophageal cancer · gastroesophageal junction adenocarcinoma · glioblastoma · lung cancer · lymphoma · malignant pleural mesothelioma · soft tissue sarcoma · invasive breast carcinoma · ovarian carcinoma · pancreatic ductal adenocarcinoma · primary peritoneal carcinoma · squamous cell carcinoma · biliary tract cancer · cholangiocarcinoma · follicular lymphoma · gastric adenocarcinoma · head and neck neoplasm · hematopoietic and lymphoid cell neoplasm · intrahepatic cholangiocarcinoma · metastatic melanoma · metastatic prostate carcinoma · non-small cell squamous lung carcinoma · pancreatic adenocarcinoma · plasma cell myeloma · prostate adenocarcinoma · refractory malignant neoplasm · Richter transformation · sarcoma · skin squamous cell carcinoma · urinary bladder carcinoma · alveolar soft part sarcoma · anal squamous cell carcinoma · cancer of unknown primary site · colorectal neoplasm · digestive system cancer · estrogen-receptor positive breast cancer · fallopian tube cancer · fallopian tube carcinoma · infiltrating bladder urothelial carcinoma · malignant mesothelioma · malignant urinary system neoplasm · metastatic malignant neoplasm in the brain · non-Hodgkin lymphoma · prostate cancer · pulmonary large cell neuroendocrine carcinoma · renal cell adenocarcinoma · renal pelvis urothelial carcinoma · appendix adenocarcinoma · B-cell chronic lymphocytic leukemia · B-cell non-Hodgkin lymphoma · bladder transitional cell carcinoma · breast adenocarcinoma · cervical adenosquamous carcinoma · cervical carcinoma · colon adenocarcinoma · colonic neoplasm · colorectal adenocarcinoma · colorectal carcinoma · esophageal adenocarcinoma · esophageal squamous cell carcinoma · fibrolamellar hepatocellular carcinoma · gallbladder adenocarcinoma · gallbladder cancer · gallbladder carcinoma · gliosarcoma · high grade malignant neoplasm · Hodgkins lymphoma · hormone receptor-positive breast cancer · hypopharynx squamous cell carcinoma · kidney medullary carcinoma · laryngeal squamous cell carcinoma · malignant glioma · malignant peritoneal mesothelioma · mesothelioma · metastatic neoplasm · myelodysplastic syndrome · nasopharyngeal carcinoma · oral cavity squamous cell carcinoma · papillary renal cell carcinoma · pheochromocytoma · rectal cancer · rectal neoplasm · skin cancer · thyroid gland undifferentiated (anaplastic) carcinoma · transitional cell carcinoma · virus associated tumor · adenocarcinoma · adult glioblastoma · adult hepatocellular carcinoma · anal canal cancer · anal canal squamous cell carcinoma · atypical teratoid rhabdoid tumor · bile duct adenocarcinoma · bile duct cancer · bladder adenocarcinoma · bladder carcinoma in situ · bladder small cell carcinoma · bladder squamous cell carcinoma · breast carcinoma · breast neoplasm · bronchogenic carcinoma · carcinosarcoma · central nervous system cancer · central nervous system melanocytic neoplasm · cervical squamous cell carcinoma · childhood malignant neoplasm · chronic lymphocytic leukemia/small lymphocytic lymphoma · chronic myeloid leukemia · chronic myelomonocytic leukemia · clear cell renal carcinoma · clear cell sarcoma · dedifferentiated chondrosarcoma · differentiated thyroid carcinoma · diffuse midline glioma, H3 K27M-mutant · digestive system carcinoma · digestive system neuroendocrine neoplasm · distal biliary tract carcinoma · endometrial carcinoma · endometrial clear cell adenocarcinoma · endometrial endometrioid adenocarcinoma · endometrial mixed adenocarcinoma · endometrial serous adenocarcinoma · endometrioid tumor · endometrium neoplasm · epithelioid sarcoma · fallopian tube clear cell adenocarcinoma · fallopian tube endometrioid adenocarcinoma · fallopian tube serous adenocarcinoma · female reproductive organ cancer · female reproductive system neoplasm · follicular lymphoma, susceptibility to · gastric neoplasm · gastroesophageal adenocarcinoma · gastrointestinal stromal tumor · Her2-receptor negative breast cancer · hereditary leiomyomatosis and renal cell cancer · hilar cholangiocarcinoma · human papillomavirus-related penile squamous cell carcinoma · IDH-wildtype glioblastoma · idiopathic pulmonary fibrosis · inflammatory breast carcinoma · invasive ductal breast carcinoma · kidney cancer · kidney neoplasm · lip and oral cavity squamous cell carcinoma · lung adenocarcinoma · lung large cell carcinoma · lung neoplasm · lung superior sulcus carcinoma · lymphoid neoplasm · lymphoproliferative syndrome · malignant biphasic mesothelioma · malignant colon neoplasm · MALT lymphoma · metachronous osteosarcoma of the bone · mismatch repair cancer syndrome · mycosis fungoides and variants · myxoid/round cell liposarcoma · nasal cavity and paranasal sinus squamous cell carcinoma · nasal cavity squamous cell carcinoma · nasopharyngeal squamous cell carcinoma · neoplasm of esophagus · neoplastic syndrome · neuroendocrine carcinoma · neuroendocrine neoplasm · oral cavity cancer · oropharyngeal carcinoma · oropharynx cancer · oropharynx squamous cell carcinoma · osteosarcoma · ovarian clear cell adenocarcinoma · ovarian endometrioid adenocarcinoma · ovarian neoplasm · ovarian seromucinous carcinoma · ovarian serous adenocarcinoma · pancreatic large cell neuroendocrine carcinoma · pancreatic neoplasm · pancreatic neuroendocrine tumor · paraganglioma · penile cancer · peritoneum cancer · pleural epithelioid mesothelioma · poorly differentiated chordoma · poorly differentiated thyroid gland carcinoma · portal vein thrombosis · primary peritoneal serous adenocarcinoma · prostate carcinoma · rectum adenocarcinoma · rhabdomyosarcoma · salivary gland cancer · small cell carcinoma · small intestine adenocarcinoma · smoldering plasma cell myeloma · squamous cell carcinoma of penis · synovial sarcoma · thymic carcinoma · undifferentiated ovarian carcinoma · ureter cancer · ureter transitional cell carcinoma · urethra cancer · urethra transitional cell carcinoma · urinary bladder neoplasm · urinary bladder small cell neuroendocrine carcinoma · uterine carcinosarcoma · uterine cervix neoplasm · vaginal squamous cell carcinoma · vulva cancer · vulvar squamous cell carcinoma · anal carcinoma · venous thromboembolism
Investigated by
Hoffmann-La Roche · Genentech, Inc. · National Cancer Institute (NCI) · Roche Pharma AG · M.D. Anderson Cancer Center · Exelixis
+513 more · The Netherlands Cancer Institute · Eli Lilly and Company · Memorial Sloan Kettering Cancer Center · NRG Oncology · Pfizer · Gustave Roussy, Cancer Campus, Grand Paris · Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest · University of Washington · Amgen · Chugai Pharmaceutical · Dana-Farber Cancer Institute · Roche-Genentech · Alliance Foundation Trials, LLC. · Cancer Research UK · Centre Leon Berard · Duke University · European Organisation for Research and Treatment of Cancer - EORTC · Fundación GECP · German Cancer Research Center · GlaxoSmithKline · Hunan Province Tumor Hospital · Italian Oncology Group for Clinical Research · Mayo Clinic · Oslo University Hospital · Roche Farma, S.A · Samsung Medical Center · Stand Up To Cancer · Sun Yat-sen University · University Hospital, Essen · Vanderbilt-Ingram Cancer Center · Washington University School of Medicine · Yale University · AIO-Studien-gGmbH · Bayer · Boehringer Ingelheim · Clovis Oncology, Inc. · Dwight Owen · Emory University · Fate Therapeutics · Fox Chase Cancer Center · French Cooperative Thoracic Intergroup · GOG Foundation · Georgetown University · Halozyme Therapeutics · Haukeland University Hospital · Helse Fonna · Helse Nord-Trøndelag HF · Helse Stavanger HF · Incyte Corporation · Ipsen · Medical College of Wisconsin · Merck Sharp & Dohme LLC · National Taiwan University Hospital · National University Hospital, Singapore · Nykode Therapeutics ASA · Oregon Health and Science University · Peter MacCallum Cancer Centre, Australia · Queen Mary University of London · Replimune, Inc. · Royal Marsden NHS Foundation Trust · SOLTI Breast Cancer Research Group · Sanofi · St. Olavs Hospital · The Methodist Hospital Research Institute · Third Affiliated Hospital, Sun Yat-Sen University · University Health Network, Toronto · University Hospital of North Norway · University Hospital, Akershus · University of Michigan Rogel Cancer Center · University of Texas Southwestern Medical Center · Vestre Viken Hospital Trust · ARCAGY/ GINECO GROUP · Aalborg University Hospital · Abramson Cancer Center at Penn Medicine · all 519 on the full record

Regulatory milestones approvals, filings & regulatory actions · 19 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Label expansions (17) US (FDA) TECENTRIQ — 2017-04-17 – 2026-05-15 fda.gov ↗
Approved EU (EMA) Tecentriq — 2017-09-20 europa.eu ↗
Approved US (FDA) TECENTRIQ — 2016-05-18 fda.gov ↗

Trials 668 · started per year

today
US approved 2016
EU approved 2017
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201120122013201420152016201720182019202020212022202320242025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 011 trials · 1 met primary
Phase 0 NCT07538128 Jan 2025 → Nov 2026 expected glioblastoma Huashan Hospital Recruiting No outcome recorded
Phase 0 NCT06098898 Nov 2023 → Nov 2024 gastric cancer Base Therapeutics (Shanghai) Co., Ltd. Unknown No outcome recorded
Phase 0 NCT05238831 Jan 2023 → May 2026 female breast carcinoma, ovarian carcinoma, pancreatic ductal adenocarcinoma, pancreatic large cell neuroendocrine carcinoma +2 OHSU Knight Cancer Institute Withdrawn No outcome recorded
Phase 0 NCT05423210 Oct 2022 → Aug 2027 expected glioblastoma Stony Brook University Recruiting No outcome recorded
Phase 0 NCT04857684 Jun 2021 → Apr 2026 overdue hepatocellular carcinoma Massachusetts General Hospital Active not recruiting No outcome recorded
Phase 0 NCT04630210 Feb 2021 → Jan 2025 breast cancer Universitaire Ziekenhuizen KU Leuven Withdrawn No outcome recorded
Phase 0 NCT04249167 Jan 2020 → Nov 2021 triple-negative breast carcinoma Mayo Clinic Withdrawn No outcome recorded
Phase 0 NCT04102618 Mar 2019 → Apr 2022 breast cancer Oncolytics Biotech Terminated No outcome recorded Stop: Enrollment
Phase 0 NCT03802604 Dec 2018 → Apr 2022 breast cancer SOLTI Breast Cancer Research Group Completed Met primary
Phase 0 NCT03208712 Nov 2017 → Aug 2018 urothelial carcinoma University of Michigan Rogel Cancer Center Terminated No outcome recorded Stop: Enrollment
Phase 1122 trials · 2 met primary
Phase 1 NCT07170592 Jan 2027 → Dec 2028 expected refractory malignant neoplasm Bionoxx Inc. Not yet recruiting No outcome recorded
Phase 1 NCT06492954 Oct 2026 → Jun 2027 expected metachronous osteosarcoma of the bone Emory University Recruiting No outcome recorded
Phase 1 NCT07190833 Mar 2026 → Dec 2028 expected refractory malignant neoplasm Bionoxx Inc. Recruiting No outcome recorded
Phase 1 NCT07113691 Jan 2026 → Jan 2030 expected small cell lung carcinoma Yale University Recruiting No outcome recorded
Phase 1 NCT06066138 Nov 2025 → Jan 2027 expected alveolar soft part sarcoma, hepatocellular carcinoma, melanoma, non-small cell lung carcinoma +1 National Cancer Institute (NCI) Recruiting No outcome recorded
Phase 1 NCT07011004 May 2025 → May 2028 expected acute myeloid leukemia Memorial Sloan Kettering Cancer Center Recruiting No outcome recorded
Phase 1 NCT06616623 Dec 2024 → Dec 2026 non-small cell lung carcinoma Dwight Owen Suspended No outcome recorded
Phase 1 NCT06488716 Dec 2024 → Nov 2025 cancer Genentech, Inc. Terminated No outcome recorded
Phase 1 NCT06551142 Sep 2024 → Oct 2028 expected neoplasm GlaxoSmithKline Recruiting No outcome recorded
Phase 1 NCT06444815 Sep 2024 → Sep 2027 expected cervical cancer, colorectal cancer, cutaneous neuroendocrine carcinoma, head and neck squamous cell carcinoma +6 KaliVir Immunotherapeutics Recruiting No outcome recorded
Show all 122 trials opens the full record — a long page
Phase 1/296 trials · 1 met primary · 7 missed
Phase 1/2 NCT07707895 Oct 2026 → Apr 2030 expected pulmonary large cell neuroendocrine carcinoma, small cell lung carcinoma Boehringer Ingelheim Not yet recruiting No outcome recorded
Phase 1/2 NCT07835737 Oct 2026 → Oct 2029 expected hepatocellular carcinoma West China Hospital Not yet recruiting No outcome recorded
Phase 1/2 NCT07407933 Mar 2026 → Nov 2028 expected small cell lung carcinoma MediLink Therapeutics (Suzhou) Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT07227597 Jan 2026 → Nov 2030 expected small cell lung carcinoma Merck Sharp & Dohme LLC Recruiting No outcome recorded
Phase 1/2 NCT07190027 Nov 2025 overdue non-small cell lung carcinoma First Affiliated Hospital of Wenzhou Medical University Not yet recruiting No outcome recorded
Phase 1/2 NCT06287775 Apr 2025 → Jul 2029 expected small cell lung carcinoma National Cancer Institute (NCI) Recruiting No outcome recorded
Phase 1/2 NCT06725121 Dec 2024 → Jun 2031 expected hepatocellular carcinoma, invasive carcinoma University Health Network, Toronto Recruiting No outcome recorded
Phase 1/2 NCT06439485 Nov 2024 → Feb 2028 expected cholangiocarcinoma M.D. Anderson Cancer Center Recruiting No outcome recorded
Phase 1/2 NCT06110572 Apr 2024 → Jun 2027 expected small cell lung carcinoma Vanderbilt-Ingram Cancer Center Recruiting No outcome recorded
Phase 1/2 NCT06067061 Apr 2024 → May 2025 triple-negative breast carcinoma Institut Curie Terminated No outcome recorded Stop: Enrollment
Phase 2322 trials · 19 met primary · 17 missed
Phase 2 NCT07322341 Oct 2026 → Nov 2030 expected non-small cell lung carcinoma University of Washington Recruiting No outcome recorded
Phase 2 NCT07654400 Jul 2026 → Dec 2027 expected small cell lung carcinoma Sichuan Baili Pharmaceutical Co., Ltd. Not yet recruiting No outcome recorded
Phase 2 NCT07018947 Jun 2026 → Jun 2031 expected hepatocellular carcinoma Fundacion Clinic per a la Recerca Biomédica Recruiting No outcome recorded
Phase 2 NCT07339059 Jun 2026 → Feb 2029 expected small cell lung carcinoma Bindu R Potugari Recruiting No outcome recorded
Phase 2 NCT07363356 Jan → Oct 2026 expected hepatocellular carcinoma Eastern Hepatobiliary Surgery Hospital Not yet recruiting No outcome recorded
Phase 2 NCT06254248 Jan 2026 → Jan 2030 expected hepatocellular carcinoma Assistance Publique - Hôpitaux de Paris Recruiting No outcome recorded
Phase 2 NCT07235293 Jan → Sep 2026 overdue colorectal cancer Kahr Bio Australia Pty Ltd Recruiting No outcome recorded
Phase 2 NCT07276100 Jan 2026 → Jan 2027 expected hepatocellular carcinoma IRCCS Azienda Ospedaliero-Universitaria di Bologna Recruiting No outcome recorded
Phase 2 NCT07224971 Dec 2025 → May 2027 expected non-small cell lung carcinoma Liza Villaruz, MD Recruiting No outcome recorded
Phase 2 NCT07239245 Nov 2025 → Nov 2027 expected hepatocellular carcinoma Cancer Institute and Hospital, Chinese Academy of Medical Sciences Recruiting No outcome recorded
Show all 322 trials opens the full record — a long page
Phase 2/312 trials · 1 missed
Phase 2/3 NCT07285850 Oct 2025 → Aug 2026 overdue hepatocellular carcinoma Eastern Hepatobiliary Surgery Hospital Recruiting No outcome recorded
Phase 2/3 NCT07293468 Apr 2024 → Mar 2034 expected hepatocellular carcinoma Tuen Mun Hospital Recruiting No outcome recorded
Phase 2/3 NCT05770102 Oct 2023 → Oct 2029 expected cancer, colorectal neoplasm, endometrium neoplasm, lymphoproliferative syndrome +1 Cancer Research UK Recruiting No outcome recorded
Phase 2/3 NCT05063552 Mar 2023 → Dec 2027 expected hypopharynx squamous cell carcinoma, laryngeal squamous cell carcinoma, lip and oral cavity squamous cell carcinoma, nasal cavity and paranasal sinus squamous cell carcinoma +5 National Cancer Institute (NCI) Active not recruiting No outcome recorded
Phase 2/3 NCT05722886 Mar 2023 → Oct 2029 expected cancer, hematopoietic and lymphoid cell neoplasm Cancer Research UK Recruiting No outcome recorded
Phase 2/3 NCT05694013 Feb 2023 → Jun 2024 cancer Hoffmann-La Roche Terminated No outcome recorded
Phase 2/3 NCT05058651 Jun 2022 → Oct 2028 expected neuroendocrine carcinoma National Cancer Institute (NCI) Recruiting No outcome recorded
Phase 2/3 NCT05141721 Feb 2022 → Mar 2027 expected colorectal neoplasm Seattle Project Corporation Active not recruiting No outcome recorded
Phase 2/3 NCT04619797 Dec 2020 → Apr 2024 non-small cell lung carcinoma Hoffmann-La Roche Completed Missed primary
Phase 2/3 NCT03178552 Sep 2017 → Jun 2027 expected non-small cell lung carcinoma Hoffmann-La Roche Active not recruiting Mixed
Phase 389 trials · 14 met primary · 18 missed
Phase 3 NCT07388524 Mar 2027 → Sep 2032 expected non-small cell lung carcinoma National Cancer Institute (NCI) Recruiting No outcome recorded
Phase 3 NCT07461675 Mar 2026 → Jun 2029 expected hepatocellular carcinoma University of Geneva, Switzerland Not yet recruiting No outcome recorded
Phase 3 NCT07166406 Feb 2026 → Mar 2029 expected hepatocellular carcinoma NRG Oncology Recruiting No outcome recorded
Phase 3 NCT06841172 Jul 2025 → Jul 2027 expected hepatocellular carcinoma Shandong Cancer Hospital and Institute Recruiting No outcome recorded
Phase 3 NCT06719336 Dec 2024 → Dec 2028 expected small cell lung carcinoma Anhui Shi, MD Not yet recruiting No outcome recorded
Phase 3 NCT06632327 Dec 2024 → Apr 2029 expected non-small cell lung carcinoma Alliance for Clinical Trials in Oncology Active not recruiting No outcome recorded
Phase 3 NCT06733038 Nov 2024 → Apr 2028 expected colorectal cancer Gruppo Oncologico del Nord-Ovest Recruiting No outcome recorded
Phase 3 NCT06031597 Sep 2023 → Dec 2025 non-small cell lung carcinoma Zhejiang Cancer Hospital Unknown No outcome recorded
Phase 3 NCT05862285 Jun 2023 → Mar 2033 expected cancer Hoffmann-La Roche Recruiting No outcome recorded
Phase 3 NCT05482516 Mar 2023 → Aug 2026 overdue bile duct adenocarcinoma, colon adenocarcinoma, gallbladder adenocarcinoma, gastric adenocarcinoma +3 Georgetown University Active not recruiting No outcome recorded
Phase 47 trials
Phase 4 NCT07059494 Jun 2026 → Aug 2027 expected hepatocellular carcinoma Icahn School of Medicine at Mount Sinai Recruiting No outcome recorded
Phase 4 NCT05689671 Dec 2023 → Mar 2026 overdue non-small cell lung carcinoma Nikolaj Frost MD Active not recruiting No outcome recorded
Phase 4 NCT06031233 Sep 2023 → Jul 2028 expected — Isala Recruiting No outcome recorded
Phase 4 NCT05717400 Mar 2023 → Aug 2024 hepatocellular carcinoma M.D. Anderson Cancer Center Terminated No outcome recorded
Phase 4 NCT05185505 Jan 2023 → Apr 2027 expected hepatocellular carcinoma The Methodist Hospital Research Institute Enrolling by invitation No outcome recorded
Phase 4 NCT04059887 Dec 2019 → Dec 2021 lung cancer Chonnam National University Hospital Completed No outcome recorded
Phase 4 NCT03285763 Oct 2017 → Apr 2022 non-small cell lung carcinoma Hoffmann-La Roche Completed No outcome recorded
Phase not applicable8 trials
— NCT07543510 May 2026 → Aug 2028 expected hepatocellular carcinoma Third Affiliated Hospital, Sun Yat-Sen University Not yet recruiting No outcome recorded
— NCT07281664 Jan 2026 → Dec 2028 expected hepatocellular carcinoma Third Affiliated Hospital, Sun Yat-Sen University Not yet recruiting No outcome recorded
— NCT05984511 Aug 2023 → Aug 2028 expected hepatocellular carcinoma Third Affiliated Hospital, Sun Yat-Sen University Recruiting No outcome recorded
— NCT04801966 Sep 2021 → Dec 2022 cancer Peter MacCallum Cancer Centre, Australia Terminated No outcome recorded Stop: Enrollment
— NCT07272265 Oct 2020 → May 2025 adult hepatocellular carcinoma Sun Yat-sen University Completed No outcome recorded
— NCT04180072 Mar 2020 → Dec 2025 overdue hepatocellular carcinoma National Health Research Institutes, Taiwan Active not recruiting No outcome recorded
— NCT03577132 Aug 2018 → May 2020 urothelial carcinoma Seoul National University Hospital Unknown No outcome recorded
— NCT03035890 Jan 2017 → Jun 2022 non-small cell lung carcinoma West Virginia University Completed No outcome recorded
Phase not stated1 trial
— NCT02589717 Nov 2015 → Aug 2016 urothelial carcinoma Genentech, Inc. Approved for marketing No outcome recorded
Comparator or background therapy122 trials
Phase 0 NCT06097962 Background Jul 2023 → Jul 2027 expected non-small cell lung carcinoma Base Therapeutics (Shanghai) Co., Ltd. Recruiting No outcome recorded
Phase 0 NCT03371992 Background Mar 2018 → Dec 2020 non-small cell lung carcinoma Nilogen Oncosystems Unknown No outcome recorded
Phase 1 NCT07545954 Background Jul 2026 → Aug 2029 expected small cell lung carcinoma Washington University School of Medicine Not yet recruiting No outcome recorded
Phase 1 NCT06719973 Background May 2025 cancer EMD Serono Research & Development Institute, Inc. Withdrawn No outcome recorded Stop: Business
Phase 1 NCT06760481 Background Apr 2025 → Sep 2028 expected high grade malignant neoplasm M.D. Anderson Cancer Center Active not recruiting No outcome recorded
Show all 122 trials opens the full record — a long page

Press releases naming this drug 334 releases

DateIssuerRelease
2026-10-09 Hoffmann-La Roche FDA approves Roche’s Tecentriq in combination with a fluoropyrimidine and oxaliplatin for the adjuvant treatment of a certain type of stage III colon cancer roche.com ↗
2026-10-08 Genentech, Inc. FDA Approves Genentech’s Tecentriq in Combination With a Fluoropyrimidine and Oxaliplatin for The Adjuvant Treatment of a Certain Type of Stage III Colon Cancer gene.com ↗
2026-10-01 Immedica Pharma AB Zepzelca® (lurbinectedin) in combination with atezolizumab approved by the MHRA as first-line maintenance therapy for extensive-stage small cell lung cancer in the United Kingdom immedica.com ↗
2026-09-24 PharmaMar The United Kingdom approves Zepzelca® (lurbinectedin) by PharmaMar in combination with atezolizumab for first-line maintenance treatment of small cell lung cancer pharmamar.com ↗
2026-09-04 Immedica Pharma AB Zepzelca® (lurbinectedin) in combination with atezolizumab approved as first-line maintenance therapy for extensive-stage small cell lung cancer in Kuwait immedica.com ↗
2026-08-14 Chugai Pharmaceutical Chugai Files for Additional Indication of Tecentriq for Adjuvant Treatment of MSI-High Colon Cancer chugai-pharm.co.jp ↗
2026-08-03 Immedica Pharma AB Zepzelca® (lurbinectedin) in combination with atezolizumab approved as first-line maintenance therapy for extensive-stage small cell lung cancer in Qatar immedica.com ↗
2026-08-03 PharmaMar Canada, Qatar and South Korea Approve PharmaMar’s Zepzelca® in combination with Atezolizumab for First-Line Maintenance Treatment of Small Cell Lung Cancer pharmamar.com ↗
2026-07-02 Treos Bio Zrt Treos Bio Presents New Translational Data Showing PolyPEPI1018 Plus Anti-PD-L1 Immunotherapy Remodels the Tumor Immune Microenvironment in MSS Colorectal Cancer treostherapeutics.com ↗
2026-06-12 Chugai Pharmaceutical Tecentriq Filed for Additional Indication as Maintenance Therapy Following Definitive Chemoradiotherapy in Locally Advanced Esophageal Cancer chugai-pharm.co.jp ↗
2026-06-11 Hoffmann-La Roche FDA grants Priority Review for Roche’s Tecentriq for a certain type of stage III colon cancer roche.com ↗
2026-06-10 Genentech, Inc. FDA Grants Priority Review for Genentech’s Tecentriq for a Certain Type of Stage III Colon Cancer gene.com ↗
Show all 334 releases opens the full record — a long page

Evidence & citations 20 cited values

Every value below carries the sentence it was read from. 797 sources stand behind the page.

FieldValueCited text
Known as Atezolizumab “Standard of Care Drugs (at investigator's discretion) may include: pembrolizumab, nivolumab, cemiplimab, durvalumab, dostarlimab, avelumab, and atezolizumab, or other immune...” NCT07224971 ↗
779

“Drug sensitivity testing will be performed on a panel of approved targeted and immunotherapeutic agents (including Apatinib, Atezolizumab + Bevacizumab, Donafenib +...” NCT07363356 ↗

“Another recent trial in patients with advanced HCC demonstrated improved survival with the combination of Atezolizumab, an immune checkpoint inhibitor (ICI), and Bevacizumab,...” NCT05137899 ↗

“In this pilot study, the investigators will investigate if Nilogen's functional ex vivo bioassay can predict therapeutic response to anti PD1 (nivolumab, pembrolizumab) or anti...” NCT03371992 ↗

“yttrium-90 radioembolization in combination with capecitabine and atezolizumab for the treatment of unresectable colorectal cancer liver metastases in individuals who have been...” NCT06555133 ↗

“TTI-621 will be given in combination with one of the following programmed death-1 (PD-1) or programmed death-ligand-1 (PD-L1) inhibitors: nivolumab, pembrolizumab, durvalumab,...” NCT02890368 ↗

“combinations such as atezolizumab plus bevacizumab, tremelimumab plus durvalumab, or monotherapies such as lenvatinib, sorafenib, tislelizumab, durvalumab, or pembrolizumab, at...” NCT06841172 ↗

“MPDL3280A (atezolizumab) is a human monoclonal antibody containing an engineered Fc-domain to optimize efficacy and safety that targets PD-L1 and blocks binding of its...” NCT02620280 ↗

“Fixed Delay Arm Delayed PD-1 + Chemo PD-1 inhibitor (e.g., Sintilimab/Keytruda/Tislelizumab/Camrelizumab/Toripalimab/Nivolumab/Atezolizumab/Sugemalimab) Immune checkpoint...” NCT07190027 ↗

“Enrolled patients received durvalumab/ Atezolizumab plus chemotherapy or target therapy treatment (durvalumab,1000mg,iv, d1, 21day as a cycle; Atezolizumab,1200mg iv, d1, 21day...” NCT05325684 ↗

“ICIs:Nivolumab/Pembrolizumab/Durvalumab/Atezolizumab/ Camrelizumab/Dupilumab/Sintilimab/Tislelizumab:administrated for patients with NSCLC requiring post-operative adjuvant therapy.” NCT05834413 ↗

Show 769 more sources

Known as 0ine2sfd9e ChEMBL registry synonym — accepted as the source's own label CHEMBL3707227 ↗
Known as Anti-PD-L1 ChEMBL registry synonym — accepted as the source's own label CHEMBL3707227 ↗
Known as Ate “Participants will receive atezolizumab (Ate) 1200 milligrams (mg) every 3 weeks (q3w) along with vemurafenib (Vem) 720 mg twice daily (BID) for 21 days in each cycle followed...” NCT01656642 ↗
Known as Atez “Atezolizumab (Atez) combined with bevacizumab (Bev) is the recommended first-line treatment for unresectable hepatocellular carcinoma (HCC).” PMID 40891895 ↗ Sep 2025
Known as atezo “This phase 1b study (NCT02431208) evaluated the safety and efficacy of the anti-programmed death-ligand 1 monoclonal antibody atezolizumab (Atezo) alone or in combination with...” PMID 37559718 ↗ Jul 2023
4

“Participants in the atezolizumab plus bevacizumab (Atezo + Bev) arm will receive up to three 3 atezolizumab doses (days 10, 31, 52) and 2 bevacizumab dose (days 10 and 31)...” NCT07018947 ↗

“Neoadjuvant therapy consists of three cycles of HAIC combined with atezolizumab and bevacizumab (atezo/bev), while adjuvant therapy includes two cycles of HAIC combined with...” NCT06739252 ↗

“This study evaluated the safety and efficacy of atezolizumab (Atezo) with or without tiragolumab (Tira) after nCRT in patients with LARC.” PMID 41529226 ↗ Jan 2026

“ipatasertib (ipat) in combination with atezolizumab (atezo) and paclitaxel (pac) or nab-paclitaxel” NCT03800836 ↗

Known as Atezolizumab component of tecentriq hybreza ChEMBL registry synonym — accepted as the source's own label CHEMBL3707227 ↗
Known as Atezolizumab-tqjc ChEMBL registry synonym — accepted as the source's own label CHEMBL3707227 ↗
Known as ATZ “4 doses of atezolizumab (ATZ) (1200 mg/dose) IV infusion every 21 days” NCT02926833 ↗
Known as MPDL3280A “A Safety and Pharmacology Study of Atezolizumab (MPDL3280A) Administered With Obinutuzumab or Tazemetostat in Participants With Relapsed/Refractory Follicular Lymphoma and...” NCT02220842 ↗
29

“A Pilot Safety Study and Single Arm Phase II Study of Gemcitabine and Cisplatin With Atezolizumab (MPDL3280A) in Patients With Metastatic and Muscle Invasive Bladder Cancer,...” NCT02989584 ↗

“A Phase l/ll, Open Label, Dose-escalation Study of Varlilumab (CDX-1127) in Combination With Atezolizumab (MPDL3280A, Anti-PD-L1) in Patients With Advanced Cancer” NCT02543645 ↗

“The Anti-PD-L1 Antibody Atezolizumab (MPDL3280A) Administered With Stereotactic Ablative Radiotherapy (SABR) in Patients With Metastatic Tumours” NCT02992912 ↗

“Atezolizumab (MPDL3280A), an engineered anti-programmed death-ligand 1 (anti-PD-L1) antibody” NCT02367794 ↗

“Atezolizumab (MPDL3280A), an engineered anti-programmed death-ligand 1 [PD-L1] antibody” NCT02410512 ↗

“Atezolizumab (MPDL3280A), an engineered anti-programmed death-ligand 1 (PD-L1) antibody” NCT02458638 ↗

“Atezolizumab (MPDL3280A), an engineered anti-programmed death-ligand 1 (PD-L1) antibody” NCT03280563 ↗

“Atezolizumab (MPDL3280A) [TECENTRIQ], an engineered anti-PDL1 antibody” NCT02409342 ↗

“Atezolizumab (MPDL3280A) [TECENTRIQ], an engineered anti-PDL1 antibody” NCT01846416 ↗

“Atezolizumab (MPDL3280A) [TECENTRIQ], an engineered anti-PDL1 antibody” NCT02302807 ↗

Show 19 more sources

Known as RG-7446 ChEMBL registry synonym — accepted as the source's own label CHEMBL3707227 ↗
Known as RO5541267; Tecentriq “RO5541267; Tecentriq” NCT02596971 ↗
Known as Tecentriq “Atezolizumab is an antibody that operates on an important receptor of the immune system (PD1/PD-L1 axis). Atezolizumab (Tecentriq®) has already been approved in a number of...” NCT05052099 ↗
23

“An Open-Label, Singe Arm, Multicenter Study to Investigate the Safety and Efficacy of Atezolizumab (Tecentriq) in Previously-Treated Patients With Locally Advanced or...” NCT03922997 ↗

“locally approved anticancer regimen containing intravenous atezolizumab (TECENTRIQ, F. Hoffmann-La Roche Ltd/Genentech) and local standard-of-care support” PMID 37076159 ↗ Apr 2023

“Enrolled Participant will receive 4 cycles of neoadjuvant Atezolizumab (Tecentriq) followed by CAPOX chemotherapy prior to surgery.” NCT05870800 ↗

“Arm B: TT-00420 tablet in combination with atezolizumab (Tecentriq®) Arm B will enroll patients with advanced biliary tract cancer.” NCT05253053 ↗

“Study of TJ004309 in Combination With Atezolizumab (Tecentriq®) in Patients With Advanced or Metastatic Cancer” NCT03835949 ↗

“four cycles of 1200 mg of atezolizumab (Tecentriq®, Roche) and 600 mg of Tiragolumab (Roche) every 3 weeks” NCT06175390 ↗

“two doses of Atezolizumab (Tecentriq), an FDA approved PD- L1 inhibitor drug, 840 mg IV” NCT05423210 ↗

“Atezolizumab (Tecentriq) intravenous (IV) 1200mg flat dose day 1 then every 3 weeks.” NCT04467723 ↗

“Atezolizumab (MPDL3280A) [TECENTRIQ], an engineered anti-PDL1 antibody” NCT02409342 ↗

“Atezolizumab (MPDL3280A) [TECENTRIQ], an engineered anti-PDL1 antibody” NCT01846416 ↗

Show 13 more sources

Known as Tecentriq (atezolizumab) “Tecentriq (atezolizumab)” NCT04157985 ↗
Known as TecentriqTM “Atezolizumab (TecentriqTM, Roche Pharma AG) is a humanized immunoglobulin (Ig) G1 monoclonal antibody that targets PD-L1 and will be applied intravenously (i.v.).” NCT05937295 ↗
Known as Tencentriq “Atezolizumab (Tencentriq)” NCT03175432 ↗
Action Inhibit “Atezolizumab inhibits PD-L1 signaling” PMID 32586767 ↗ May 2020
Modality Monoclonal antibody “The humanized monoclonal antibody atezolizumab targets programmed death-ligand 1” PMID 30347025 ↗ Mar 2019
Route Intravenous “Atezolizumab will be administered at a dose of 1200 mg by IV infusion” NCT00781612 ↗
Target CD274 “PD-L1 targeting antibody MPDL3280A” NCT02478099 ↗