drugset / Trial / NCT07113691

Iadademstat + SBRT With Atezo in ES-SCLC

NCT07113691

NaSingle-groupOpen-labelTreatment

Summary

This is a phase 1b dose escalation, open-label, non-randomized study of participants with residual, progressive or recurrent ES-SCLC who previously received platinum-based chemotherapy with or without immune checkpoint inhibitor therapy; participants who have achieved only stable disease at the completion of initial platinum-based treatment are eligible for enrollment.

Timeline

Start
2026-01-20
Primary completion
2030-01
Completion
2030-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Atezolizumab Monoclonal antibody 1680 mg Intravenous
Subject Iadademstat Small molecule 600 ug Oral