drugset / Trial / NCT03973333
Safety and Efficacy of IMC-C103C as Monotherapy and in Combination With Atezolizumab
Non-randomizedSequentialOpen-labelTreatment
Summary
IMC-C103C is an immune mobilizing monoclonal T cell receptor against cancer (ImmTAC ®) designed for the treatment of cancers positive for the tumor-associated antigen MAGE-A4. This is a first-in-human trial designed to evaluate the safety and efficacy of IMC-C103C in adult patients who have the appropriate HLA-A2 tissue marker and whose cancer is positive for MAGE-A4.
Timeline
- Start
- 2019-05-17
- Primary completion
- 2023-09-25
- Completion
- 2023-09-25
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Atezolizumab | Monoclonal antibody | — | Intravenous |
| Subject | IMC-C103C | Protein / enzyme biologic | — | Intravenous |