drugset / Trial / NCT04801966

Safety and Oversight of the Individually Tailored Treatment Approach: A Novel Pilot Study

NCT04801966

NaSingle-groupOpen-labelTreatment

Summary

This study is looking at outcomes in people with advanced cancers who have exhausted standard treatment options and are accessing off indication or unregistered drugs or combinations of drugs through compassionate access from the manufacturer.

Timeline

Start
2021-09-23
Primary completion
2022-12-30
Completion
2022-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Abemaciclib Small molecule 150 mg
Subject Alpelisib Small molecule 300 mg
Subject Atezolizumab Monoclonal antibody 1200 mg Intravenous
Subject Binimetinib Small molecule 45 mg
Subject Cobimetinib Small molecule 60 mg
Subject Dabrafenib Small molecule 150 mg
Subject Encorafenib Small molecule 450 mg
Subject Nivolumab Monoclonal antibody 240 mg Intravenous
Subject Olaparib Small molecule 300 mg
Subject Palbociclib Small molecule 125 mg
Subject Pembrolizumab Monoclonal antibody 200 mg Intravenous
Subject Ribociclib Small molecule 600 mg
Subject Talazoparib Small molecule 1 mg
Subject Trametinib Small molecule 2 mg
Subject Vemurafenib Small molecule 960 mg

Indications