Drugs / NYX-2925
last change Jun 2022 re-read 3 minutes ago

NYX-2925

Small molecule

Developed for
diabetic polyneuropathy · fibromyalgia
Investigated by
Aptinyx · Worldwide Clinical Trials · Syneos Health · inVentiv Health Clinical

Trials 4

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 24 trials · 2 missed
Phase 2 NCT04146896 Nov 2019 → Feb 2022 diabetic polyneuropathy Aptinyx Completed Missed primary
Phase 2 NCT04147858 Nov 2019 → Jun 2022 fibromyalgia Aptinyx Completed Missed primary
Phase 2 NCT03249103 Aug 2017 → Apr 2019 fibromyalgia Aptinyx Completed No outcome recorded
Phase 2 NCT03219320 Jun 2017 → Nov 2018 diabetic polyneuropathy Aptinyx Completed No outcome recorded
Comparator or background therapy1 trial
Phase 1 NCT02834741 Comparator Jul 2016 → Mar 2017 — Aptinyx Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

FieldValueCited text
Known as NYX-2925 ClinicalTrials.gov intervention name — accepted as the source's own label NCT03249103 ↗
4

NCT02834741 ↗

NCT03219320 ↗

NCT04147858 ↗

NCT04146896 ↗

Action Activate “NYX-2925 is a small molecule that acts as an N-methyl-D-aspartate receptor (NMDAR) functional glycine-site partial agonist.” NCT02834741 ↗
Modality Small molecule “NYX-2925 is a small molecule that acts as an N-methyl-D-aspartate receptor (NMDAR) functional glycine-site partial agonist.” NCT02834741 ↗
Route Oral “study of oral NYX-2925 in healthy volunteers” NCT02834741 ↗