drugset / Trial / NCT03249103

Evaluate the Efficacy and Safety of NYX-2925 in Subjects With Fibromyalgia

NCT03249103 ↗

Phase 2 Completed 22 enrolled Aptinyx inVentiv Health Clinical · collab
NaSingle-groupOpen-labelTreatment

Summary

The primary objective is to determine whether daily dosing with NYX-2925 changes markers of central pain processing in subjects with fibromyalgia by evaluating changes in evoked pain, and visual stimulation, functional magnetic resonance imaging (fMRI), resting state function connectivity magnetic resonance imaging (rs-fcMRI) and proton magnetic resonance spectroscopy (H-MRS) in fibromyalgia subjects on active drug versus placebo.

Timeline

Start
2017-08-14
Primary completion
2019-04-18
Completion
2019-04-18

Drugs

EvaluationDrugModalityDoseRoute
Subject NYX-2925 Small molecule 20 mg —
Subject NYX-2925 Small molecule 200 mg —

Indications