Drugs / TTP273
last change Jun 2017 re-read 3 minutes ago

TTP273

Developed for
type 2 diabetes mellitus
Investigated by
vTv Therapeutics

Trials 1

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 2 NCT02653599 Dec 2015 → Nov 2016 type 2 diabetes mellitus vTv Therapeutics Completed Met primary

News releases announcing trial results or a regulatory action · 4

DateIssuerRelease
2017-06-11 vTv Therapeutics Results vTv Therapeutics Presents Data Highlighting Further Potential of TTP273 at American Diabetes Association 77th Scientific Sessions vtvtherapeutics.com ↗
vTv Therapeutics Inc. (vTv) (Nasdaq: VTVT) today announced that results from a Phase 2 clinical study of TTP273, an investigational, oral small molecule GLP-1 receptor (GLP-1R) agonist for the treatment of Type 2 diabetes, were presented at the American Diabetes Association 77 th Scientific Sessions.
2016-12-14 vTv Therapeutics Results vTv Therapeutics Announces Positive Topline Results from Phase 2 Study of TTP273 in Type 2 Diabetes vtvtherapeutics.com ↗
TTP273 demonstrated a statistically significant reduction in HbA1c.
2016-04-20 vTv Therapeutics Results vTv Therapeutics Presents Data on Two Diabetes Candidates at Keystone Symposia on New Therapeutics for Diabetes and Obesity vtvtherapeutics.com ↗
Data featured in an oral presentation show TTP273 is the first GLP-1R agonist without significant gastrointestinal side effects
2016-02-22 vTv Therapeutics Results vTv Therapeutics Reports Preclinical and Clinical Results on its Diabetes Candidate TTP273 vtvtherapeutics.com ↗
Data presented showed that TTP273, vTv’s orally bioavailable GLP-1R agonist currently being evaluated in a Phase 2 trial, shows “functional selectivity” for a particular subset of the full GPCR signaling repertoire.

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as TTP273 ClinicalTrials.gov intervention name — accepted as the source's own label NCT02653599 ↗
Route Oral “administered orally” NCT02653599 ↗