drugset / Trial / NCT02653599

A Study to Evaluate Safety and Efficacy of TTP273 for 12 Weeks in Subjects With Type 2 Diabetes

NCT02653599 ↗

Phase 2 Completed 174 enrolled vTv Therapeutics
RandomizedParallel-groupDouble-blindTreatment

Summary

This trial is a multi-center, randomized, double-blind, placebo-controlled parallel group, Phase 2 study in subjects with Type 2 diabetes mellitus on a stable dose of metformin to evaluate the safety and efficacy of TTP273 versus placebo glucose control and body weight following administration for 3 months.

Timeline

Start
2015-12
Primary completion
2016-11
Completion
2017-01

Outcome

Met primary endpoint

release “TTP273, an oral small molecule GLP-1R agonist, which met its primary endpoint and demonstrated a statistically significant reduction in HbA1c” vtvtherapeutics.com ↗

Drugs

EvaluationDrugModalityDoseRoute
Subject TTP273 Unknown 150 mg Oral
Subject TTP273 Unknown 300 mg Oral