Drugs / GLPG0259
last change Nov 2012 re-read 2 minutes ago

GLPG0259

Small molecule targets MAPKAPK5 via inhibition

Developed for
rheumatoid arthritis
Investigated by
Lakefront Biotherapeutics NV

Trials 5 · a red edge is where a trial was stopped

2009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 14 trials
Phase 1 NCT01322451 Nov → Dec 2010 Lakefront Biotherapeutics NV Completed No outcome recorded
Phase 1 NCT01024517 Nov → Dec 2009 Lakefront Biotherapeutics NV Completed No outcome recorded
Phase 1 NCT00989703 Sep → Nov 2009 Lakefront Biotherapeutics NV Completed No outcome recorded
Phase 1 NCT00905138 Mar → Jun 2009 Lakefront Biotherapeutics NV Completed No outcome recorded
Phase 21 trial
Phase 2 NCT01211249 Oct 2010 → Apr 2011 rheumatoid arthritis Lakefront Biotherapeutics NV Completed No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 7 sources stand behind the page.

FieldValueCited text
Known as GLPG0259 ClinicalTrials.gov intervention name — accepted as the source's own label NCT00905138
4

NCT01322451

NCT01211249

NCT00989703

NCT01024517

Action Inhibit “Oral administration of GLPG0259, an inhibitor of MAPKAPK5, a new target for the ” PMID 23161899 Nov 2012
Modality Small molecule CHEMBL5095028
Route Oral “multiple oral doses” NCT00905138
Target MAPKAPK5 “Oral administration of GLPG0259, an inhibitor of MAPKAPK5, a new target for the ” PMID 23161899 Nov 2012