Drugs / AZD5004
last change 13 days ago re-read 9 days ago

AZD5004

Developed for
type 2 diabetes mellitus · obesity disorder
Investigated by
AstraZeneca · Parexel · Eccogene · Fortrea Clinical Research Unit Inc. · Quotient Sciences

Trials 12

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 111 trials
Phase 1 NCT07444424 Mar → Jul 2026 — AstraZeneca Completed No outcome recorded
Phase 1 NCT07455825 Mar → Jun 2026 — AstraZeneca Completed No outcome recorded
Phase 1 NCT06988553 Jun → Nov 2025 obesity disorder, type 2 diabetes mellitus Eccogene Completed No outcome recorded
Phase 1 NCT06942936 May 2025 → Jan 2026 — AstraZeneca Completed No outcome recorded
Phase 1 NCT06996886 May → Jul 2025 — AstraZeneca Completed No outcome recorded
Phase 1 NCT06948747 May → Oct 2025 — AstraZeneca Completed No outcome recorded
Phase 1 NCT06857695 Mar → May 2025 — AstraZeneca Completed No outcome recorded
Phase 1 NCT06813781 Dec 2024 → Oct 2025 — AstraZeneca Completed No outcome recorded
Phase 1 NCT06742762 Dec 2024 → Apr 2025 impaired renal function disease AstraZeneca Completed No outcome recorded
Phase 1 NCT06703658 Nov 2024 → Mar 2025 type 2 diabetes mellitus AstraZeneca Completed No outcome recorded
Phase 21 trial
Phase 2 NCT06579105 Oct 2024 → Dec 2025 type 2 diabetes mellitus AstraZeneca Completed No outcome recorded

News releases announcing trial results or a regulatory action · 2

DateIssuerRelease
2026-02-10 Eccogene Results Eccogene Announces Positive Topline Results from Phase 1b Trial of Elecoglipron (AZD5004/ECC5004), an Oral GLP-1 Receptor Agonist, in Adult Participants Living with Obesity/Overweight, with or without Type 2 Diabetes in China eccogene.com ↗
The results demonstrated a safety and tolerability profile consistent with the GLP-1 receptor agonist (GLP-1RA) class.
2022-11-03 Eccogene Regulatory Eccogene Announces US IND Approval for GLP-1 Receptor Agonist ECC5004 eccogene.com ↗
Eccogene announced that the U.S. Food and Drug Administration (FDA) has approved the investigational new drug (IND) application to commence a Phase I trial of its glucagon-like peptide 1 receptor agonist (GLP-1 RA) ECC5004 for type 2 diabetes mellitus (T2DM).

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 12 sources stand behind the page.

FieldValueCited text
Known as AZD5004 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06742762 ↗
11

NCT06942936 ↗

NCT06948747 ↗

NCT06555822 ↗

NCT06857695 ↗

NCT06703658 ↗

NCT07455825 ↗

NCT06996886 ↗

NCT07444424 ↗

NCT06988553 ↗

NCT06579105 ↗

Show 1 more source

Route Oral “Participants will receive oral tablets of AZD5004 in Part A and Part B of the study as per arms they are assigned.” NCT06555822 ↗