drugset / Trial / NCT06942936
A Study to Investigate the Impact of Multiple Doses of Itraconazole on AZD5004 in Healthy Participants and Multiple Doses of AZD5004 on Combined Oral Ethinyl Oestradiol and Levonorgestrel in Healthy Female Participants
Non-randomizedSequentialOpen-labelTreatment
Summary
The purpose of this study is to assess the impact of multiple doses of itraconazole on the pharmacokinetics (PK) of AZD5004 in healthy participants (Part A), and to assess the impact of multiple doses of AZD5004 on the PK of Combined Oral Contraceptives (COCs) in healthy female participants (Part B).
Timeline
- Start
- 2025-05-28
- Primary completion
- 2026-01-28
- Completion
- 2026-01-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | AZD5004 | Unknown | — | Oral |
| Subject | Itraconazole | Small molecule | — | Oral |
| Subject | Levonorgestrel | Small molecule | 0.15 mg | Oral |
| Subject | ethinyl estradiol | Small molecule | 0.03 mg | Oral |
Indications
No indication recorded.