Drugs / Ibuzatrelvir
last change Jun 2026 re-read 2 minutes ago

Ibuzatrelvir

also known as PF-07817883

Small molecule

Developed for
COVID-19
Investigated by
Pfizer

Trials 12 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 19 trials
Phase 1 NCT07552779 Apr → Jun 2026 overdue COVID-19, pneumonia Pfizer Active not recruiting No outcome recorded
Phase 1 NCT07235137 Oct → Nov 2025 Pfizer Completed No outcome recorded
Phase 1 NCT06693518 Nov 2024 → Jan 2025 COVID-19 Pfizer Completed No outcome recorded
Phase 1 NCT06646042 Oct 2024 → Jan 2025 Pfizer Completed No outcome recorded
Phase 1 NCT06586216 Sep 2024 → Feb 2025 COVID-19 Pfizer Completed No outcome recorded
Phase 1 NCT06122194 Nov 2023 → Jan 2024 Pfizer Completed No outcome recorded
Phase 1 NCT05884554 Jun 2023 → Jun 2024 COVID-19 Pfizer Completed No outcome recorded
Phase 1 NCT05822440 Apr → Jul 2023 Pfizer Completed No outcome recorded
Phase 1 NCT05580003 Oct 2022 → Sep 2023 Pfizer Completed No outcome recorded
Phase 21 trial
Phase 2 NCT05799495 May → Sep 2023 COVID-19 Pfizer Completed No outcome recorded
Phase 32 trials
Phase 3 NCT07013474 Jul 2025 → Sep 2027 expected COVID-19 Pfizer Recruiting No outcome recorded
Phase 3 NCT06679140 Dec 2024 → Oct 2027 expected COVID-19 Pfizer Recruiting No outcome recorded

Evidence & citations 5 cited values

Every value below carries the sentence it was read from. 15 sources stand behind the page.

FieldValueCited text
Known as ibuzatrelvir Ibuzatrelvir is an orally bioavailable SARS-CoV-2 Mpro inhibitor with demonstrated in vitro antiviral activity and low potential for safety concerns, including drug-drug interactions.” PMID 39486089 Mar 2025
6

Ibuzatrelvir 600 mg + Dabigatran Etexilate 150 mg” NCT06693518

NCT07552779

NCT07013474

NCT06646042

NCT07235137

NCT06679140

Known as PF-07817883 ClinicalTrials.gov intervention name — accepted as the source's own label NCT05799495
5

NCT05580003

NCT06586216

NCT05884554

NCT05822440

NCT06122194

Action Inhibit “SARS-CoV-2 Mpro inhibitor” PMID 41796210 Mar 2026
Modality Small molecule CHEMBL5591580
Route Oral “Participants will take PF-07817883 by mouth up to 2 times a day.” NCT05580003