A Study to Learn Safety and Blood Levels of PF-07817883 in Healthy People

Summary

The purpose of this clinical trial is to learn if the study medicine (called PF-07817883) is safe and how it goes in and out of the body in healthy people. PF-07817883 is for the potential treatment of COVID-19. Participants will take PF-07817883 by mouth up to 2 times a day. This study may also evaluate how much PF-07817883 gets into the body when taken as pill. We may study if people's diets can affect this study medicine. We may also examine how PF-07817883 is processed and removed by the human body. Finally, we may look into if PF-07817883 has potential to interact with midazolam.

Timeline

Start

2022-10-17

Primary completion

2023-09-15

Completion

2023-09-15

Publications

• Singh RSP, Toussi SS, Hackman F, Shahbazi M, Prybylski J, Sahasrabudhe SA, Crownover P, Kadar EP, George BT, Alami NN, Bergman A. A Multipart Phase 1 Study to Assess Safety and Pharmacokinetics of Ibuzatrelvir in Healthy Participants and Dose Selection for a Dose-Ranging Study. Clin Transl Sci. 2026 Jul;19(7):e70659. doi: 10.1111/cts.70659.

Drugs

Indications

No indication recorded.