Drugs / ACTINIUM DOTATATE
ACTINIUM DOTATATE
also known as
RYZ101 · 225Ac-DOTATATE · 225ac-oxodotreotide · ACTINIUM AC 225 DOTATATE · Actinium oxodotreotide ac-225 · Oxodotreotide ac-225
Trials 5 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT06411301 | Oct 2024 → Oct 2026 | plasma cell myeloma | Jules Bordet Institute | Withdrawn | No outcome recorded |
| Phase 1 | NCT05595460 | Oct 2022 → Jul 2027 expected | small cell lung carcinoma | RayzeBio, Inc. | Active not recruiting | No outcome recorded |
| Phase 1/22 trials | ||||||
| Phase 1/2 | NCT07150806 | Nov 2025 → Dec 2026 expected | meningioma | Joshua Palmer | Recruiting | No outcome recorded |
| Phase 1/2 | NCT06590857 | Jul 2024 → Oct 2028 expected | Her2-receptor negative breast cancer, estrogen-receptor positive breast cancer | RayzeBio, Inc. | Active not recruiting | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT05477576 | Mar 2022 → Dec 2026 expected | carcinoid tumor, pancreatic neuroendocrine tumor | RayzeBio, Inc. | Recruiting | No outcome recorded |
Evidence & citations 9 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | ACTINIUM DOTATATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL6068772 ↗ |
| Known as | 225Ac-DOTATATE | “Phase 1b/2 Open-label Trial of 225Ac-DOTATATE (RYZ101) in Subjects With Estrogen Receptor-positive (ER+), Human Epidermal Growth Factor Receptor 2 (HER2)-Negative, Locally...” NCT06590857 ↗2“I. To estimate the efficacy of 225Ac-DOTATATE (RYZ101) therapy in the treatment of patients with progressive or recurrent grade 1-3 intracranial meningioma as measured by the...” NCT07150806 ↗ |
| Known as | 225ac-oxodotreotide | ChEMBL registry synonym — accepted as the source's own label CHEMBL6068772 ↗ |
| Known as | ACTINIUM AC 225 DOTATATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL6068772 ↗ |
| Known as | Actinium oxodotreotide ac-225 | ChEMBL registry synonym — accepted as the source's own label CHEMBL6068772 ↗ |
| Known as | Oxodotreotide ac-225 | ChEMBL registry synonym — accepted as the source's own label CHEMBL6068772 ↗ |
| Known as | RYZ101 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT05595460 ↗ |
| Modality | Other / unclassified | “It is a type of radioconjugate and a type of somatostatin analog.” NCT07150806 ↗ |
| Route | Intravenous | “Two intravenous infusions every 6 weeks (Q6W)” NCT06411301 ↗ |