drugset / Trial / NCT05595460

Study of RYZ101 in Combination With SoC in Subjects With SSTR+ ES-SCLC

NCT05595460

Phase 1 Active not recruiting 21 enrolled RayzeBio, Inc.
NaSingle-groupOpen-labelTreatment

Summary

This study aims to determine the safety, preliminary antitumor activity, and pharmacokinetics (PK) of RYZ101 in combination with standard of care (SoC) therapy consisting of carboplatin + etoposide + atezolizumab in untreated subjects with somatostatin receptor expressing (SSTR+) ES-SCLC.

Timeline

Start
2022-10-10
Primary completion
2027-07
Completion
2027-07

Drugs

EvaluationDrugModalityDoseRoute
Subject ACTINIUM DOTATATE Other / unclassified
Background Atezolizumab Monoclonal antibody
Background Carboplatin Small molecule
Background Etoposide Small molecule