Drugs / EPCAM-targeted CAR-T cells
last change Nov 2019 re-read 3 minutes ago

EPCAM-targeted CAR-T cells

Cell therapy targets EPCAM via depletion

Developed for
gastric neoplasm · liver cancer
Investigated by
Sinobioway Cell Therapy Co., Ltd.

Trials 2

201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
— NCT02729493 Nov 2015 → Nov 2019 liver cancer Sinobioway Cell Therapy Co., Ltd. Unknown No outcome recorded
— NCT02725125 Nov 2015 → Nov 2019 gastric neoplasm Sinobioway Cell Therapy Co., Ltd. Unknown No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as EPCAM-targeted CAR-T cells ClinicalTrials.gov intervention name — accepted as the source's own label NCT02725125 ↗
1

NCT02729493 ↗

Action Deplete “the CAR-EPCAM-modified T cells can recognize and kill tumor cells in the body” NCT02725125 ↗
Modality Cell therapy “infusion of the patient's own T cells that have been genetically modified to express a chimeric antigen receptor(CAR)” NCT02725125 ↗
Target EPCAM “a chimeric antigen receptor(CAR)that will bind to tumour cells that express the EPCAM protein on the cell surface” NCT02729493 ↗