drugset / Trial / NCT02725125
Study Evaluating the Efficacy and Safety With CAR-T for Stomach Cancer
NaSingle-groupOpen-labelTreatment
Summary
This single-arm, multicenter Phase 2 trial will treat the patients who have relapsed or refractory stomach cancer with an infusion of the patient's own T cells that have been genetically modified to express a chimeric antigen receptor(CAR) that will bind to tumor cells that express the EPCAM protein on the cell surface.The study will determine if these modified T cells help the body's immune system eliminate tumor cells.The trial will also study the safety of treatment with CAR-T, how long CAR-T cells stay in the patient's body and the impact of this treatment on survival.
Timeline
- Start
- 2015-11
- Primary completion
- 2019-11
- Completion
- 2019-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | EPCAM-targeted CAR-T cells | Cell therapy | 100 ml | Other |