Drugs / AZD5492
last change May 2025 re-read 3 minutes ago

AZD5492

Developed for
B-cell neoplasm · idiopathic inflammatory myopathy · rheumatoid arthritis · systemic lupus erythematosus
Investigated by
AstraZeneca · Fortrea

Trials 2

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT06916806 May 2025 → May 2027 expected idiopathic inflammatory myopathy, rheumatoid arthritis, systemic lupus erythematosus AstraZeneca Recruiting No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT06542250 Sep 2024 → Feb 2028 expected B-cell neoplasm AstraZeneca Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 1

DateIssuerRelease
2024-11-07 AstraZeneca Results AstraZeneca showcases strength of haematology portfolio and pipeline at ASH 2024 astrazeneca.com ↗
An oral presentation will share preclinical data demonstrating the anti-tumour activity of AZD5492, a next-generation CD8 selective, CD20-targeting T-cell engager, designed using AstraZeneca’s innovative Target Induced T-cell Activating Nanobody (TITAN) platform.

All press releases naming this drug 1 release

DateIssuerRelease

Evidence & citations 2 cited values

Every value below carries the sentence it was read from. 2 sources stand behind the page.

FieldValueCited text
Known as AZD5492 ClinicalTrials.gov intervention name — accepted as the source's own label NCT06542250 ↗
1

NCT06916806 ↗

Route Subcutaneous “which is administered subcutaneously” NCT06542250 ↗