drugset / Trial / NCT06542250

A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

NCT06542250 ↗

Phase 1/2 Recruiting 174 enrolled AstraZeneca
NaSequentialOpen-labelTreatment

Summary

This is a Phase I/II study designed to evaluate if experimental T cell engaging antibody targeting CD20 AZD5492 is safe, tolerable and efficacious in participants with Relapsed or Refractory B-Cell Malignancies.

Timeline

Start
2024-09-18
Primary completion
2028-02-14
Completion
2028-02-14

Drugs

EvaluationDrugModalityDoseRoute
Subject AZD5492 Unknown — Subcutaneous

Indications