Drugs / Bomedemstat
Bomedemstat
also known as
IMG-7289 · Bomedemstat ditosylate · BOMEDEMSTAT TOSYLATE · IMG-241 bis-tosylate salt · IMG-7289 DITOSYLATE · MK-3543
Small molecule targets KDM1A via inhibition
Trials 16 · a red edge is where a trial was stopped
Evidence & citations 11 cited values
Every value below carries the sentence it was read from. 17 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Bomedemstat | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04254978 ↗ |
| Known as | Bomedemstat ditosylate | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297289 ↗ |
| Known as | BOMEDEMSTAT TOSYLATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297289 ↗ |
| Known as | IMG-241 bis-tosylate salt | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297289 ↗ |
| Known as | IMG-7289 | “This is an open-label, Phase 2 study of bomedemstat (IMG-7289), an inhibitor of lysine-specific demethylase 1 (LSD1), in combination with JAK inhibition (JAKi) in patients with...” NCT05569538 ↗4“An Extension Study of Bomedemstat (IMG-7289/MK-3543) in Participants With Myeloproliferative Neoplasms” NCT05223920 ↗ “Bomedemstat (IMG-7289) in Combination With Momelotinib in Patients With Myelofibrosis” NCT07424950 ↗ |
| Known as | IMG-7289 DITOSYLATE | ChEMBL registry synonym — accepted as the source's own label CHEMBL4297289 ↗ |
| Known as | MK-3543 | “An Extension Study of Bomedemstat (IMG-7289/MK-3543) in Participants With Myeloproliferative Neoplasms” NCT05223920 ↗ |
| Action | Inhibit | “Lysine-specific histone demethylase 1 inhibitor” CHEMBL4297289 ↗1“lysine-specific demethylase 1 (LSD1) inhibitor” NCT02842827 ↗ |
| Modality | Small molecule | — CHEMBL4297289 ↗ |
| Route | Oral | “oral administration” NCT02842827 ↗ |
| Target | KDM1A | “Lysine-specific histone demethylase 1 inhibitor” CHEMBL4297289 ↗ |