drugset / Trial / NCT05597306

Venetoclax and Bomedemstat in Patients With Relapsed/Refractory Acute Myeloid Leukemia

NCT05597306

Non-randomizedSequentialOpen-labelTreatment

Summary

This study aims to learn about the safety, tolerability, and different dose levels' safety profiles of Venetoclax and Bomedemstat (VenBom) combination therapy in participants with relapsed or refractory acute myeloid leukemia.

Timeline

Start
2022-11-19
Primary completion
2026-11-19
Completion
2026-11-19

Drugs

EvaluationDrugModalityDoseRoute
Subject Bomedemstat Small molecule 0.375 mg/kg Oral
Subject Bomedemstat Small molecule 0.75 mg/kg Oral
Subject Bomedemstat Small molecule 1.5 mg/kg Oral
Subject Bomedemstat Small molecule 3 mg/kg Oral
Subject Venetoclax Small molecule 200 mg Oral
Subject Venetoclax Small molecule 400 mg Oral