Drugs / DESOXYRIBONUCLEASE
DESOXYRIBONUCLEASE
also known as
Deoxyribonuclease · DNase · Deanase · Deoxyribonuclease i · Deoxyribonuclease i bovine · Deoxyribonuclease, bovine · Dinase · Dornavac · +1 more
Trials 1 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 4 | NCT07095361 | Sep 2025 → Sep 2028 expected | empyema, pleural empyema, respiratory tract infectious disorder | University of North Carolina, Chapel Hill | Recruiting | No outcome recorded |
Also used as a comparator or background therapy in 1 trial
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 4 | NCT03468933 Comparator | Nov 2017 → Dec 2019 | empyema, pleuropneumonia | Tulane University | Completed | No outcome recorded |
Evidence & citations 12 cited values
Every value below carries the sentence it was read from. 3 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | DESOXYRIBONUCLEASE | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201459 ↗ |
| Known as | Deanase | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201459 ↗ |
| Known as | Deoxyribonuclease | “instillation of intrapleural tissue Plasminogen Activator (TPA) and human recombinant Deoxyribonuclease (DNase) for the management of empyema or complicated parapneumonic...” NCT03468933 ↗2“Deoxyribonuclease (DNase) 5mg will be administered once a day as intrapleural enzyme therapy (IET) for 3 consecutive days.” NCT07095361 ↗ |
| Known as | Deoxyribonuclease i | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201459 ↗ |
| Known as | Deoxyribonuclease i bovine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201459 ↗ |
| Known as | Deoxyribonuclease, bovine | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201459 ↗ |
| Known as | Dinase | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201459 ↗ |
| Known as | DNase | “instillation of intrapleural tissue Plasminogen Activator (TPA) and human recombinant Deoxyribonuclease (DNase) for the management of empyema or complicated parapneumonic...” NCT03468933 ↗1“Deoxyribonuclease (DNase) 5mg will be administered once a day as intrapleural enzyme therapy (IET) for 3 consecutive days.” NCT07095361 ↗ |
| Known as | Dornavac | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201459 ↗ |
| Known as | Pancreatic dornase | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201459 ↗ |
| Modality | Protein / enzyme biologic | “human recombinant deoxyribonuclease” NCT03468933 ↗ |
| Route | Other | “receive intrapleural combination” NCT03468933 ↗ |