Drugs / Lutein
Lutein
also known as
All-trans-lutein · All-trans-xanthophyll · Bo-xan · E 161 · E 161b · E-161B(I) · Floraglo · Floraglo lutein · +13 more
Trials 10 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 01 trial | ||||||
| Phase 0 | NCT06270680 | Aug → Nov 2024 | brain injury, carotenemia | Penn State University | Completed | No outcome recorded |
| Phase 11 trial | ||||||
| Phase 1 | NCT00121589 | Jul 2005 → Aug 2007 | macular degeneration | National Eye Institute (NEI) | Completed | No outcome recorded |
| Phase 1/21 trial | ||||||
| Phase 1/2 | NCT00029289 | Apr 2001 → Oct 2002 | retinitis pigmentosa | National Center for Complementary and Integrative Health (NCCIH) | Completed | No outcome recorded |
| Phase 23 trials | ||||||
| Phase 2 | NCT03750968 | Sep 2019 → Jan 2022 | nutritional deficiency disease, pregnancy disorder | Paul S. Bernstein | Completed | No outcome recorded |
| Phase 2 | NCT02062034 | Feb 2011 → Nov 2013 | diabetic retinopathy, type 2 diabetes mellitus | University of Guadalajara | Completed | No outcome recorded |
| Phase 2 | NCT00006202 | Sep 2000 → Aug 2003 | macular degeneration | National Eye Institute (NEI) | Completed | No outcome recorded |
| Phase 32 trials | ||||||
| Phase 3 | NCT03702374 | Sep 2018 → Nov 2020 | diabetic retinopathy | University of Guadalajara | Completed | No outcome recorded |
| Phase 3 | NCT00346333 | Jul 2003 → Dec 2008 | retinitis pigmentosa | National Eye Institute (NEI) | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT00449917 | Sep 2006 → Jul 2007 | — | PiLeJe | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT03340103 | Oct 2018 → Oct 2019 | — | Sooft Italia | Withdrawn | No outcome recorded |
Also used as a comparator or background therapy in 6 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 1/23 trials | ||||||
| Phase 1/2 | NCT03959592 Comparator | Aug 2019 → Nov 2021 | glaucoma | Felipe Medeiros, MD | Terminated | No outcome recorded |
| Phase 1/2 | NCT01056094 Comparator | Apr 2010 → Jul 2012 | — | Peking University | Unknown | No outcome recorded |
| Phase 1/2 | NCT01048476 Comparator | Sep 2009 → Apr 2012 | age-related macular degeneration | Peking University | Unknown | No outcome recorded |
| Phase 21 trial | ||||||
| Phase 2 | NCT04071977 Comparator | Mar 2020 → Oct 2021 | diabetes mellitus, diabetic retinopathy | University of Guadalajara | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT00345176 Comparator | Sep 2006 → Oct 2012 | age-related macular degeneration, cataract | National Eye Institute (NEI) | Completed | No outcome recorded |
| Phase not applicable1 trial | ||||||
| — | NCT00914576 Comparator | Apr 2011 → Jul 2013 | — | Medical University of Vienna | Completed | No outcome recorded |
Evidence & citations 24 cited values
Every value below carries the sentence it was read from. 17 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Lutein | “It consists in a tablet with lutein (10 mg), astaxanthin (4 mg), Zeaxanthin (1mg), vitamin C (L-ascorbic acid 180mg), vitamin E (DL-alpha tocopherol 30mg), zinc (zinc oxide...” NCT03702374 ↗15“(1 mg copper, 20 mg zinc, 180 mg vitamin C, 30 mg vitamin E, 1 mg zeaxanthin, 4 mg astaxanthin, 10 mg lutein) daily of oral, all of them in one Tablet for 24 weeks” NCT02062034 ↗ “LUTEIN ofta 0,5 gocce, containing a solution of 5% Lutein and 2,5% Zeaxanthin with excipients (Corn starch, glucose, potassium sorbate, xanthan gum, citric acid)” NCT03340103 ↗ “Each dose will consist of one supplement capsule containing 10 mg lutein, 2 mg zeaxanthin, 10 mg mesozeaxanthin, 50mg EPA, 250mg DHA.” NCT06270680 ↗ “containing: Lutein 12mg, Vitamin C 300mg, Zinc 10mg, Ginko Biloba 10mg, Flavonoids 25mg, Fish oil 300mg” NCT00914576 ↗ “Softgel active ingredients: Lutein 10 mg and Zeaxanthin 2 mg in safflower oil” NCT03750968 ↗ “tablet with lutein (10 mg)” NCT04071977 ↗ |
| Known as | All-trans-lutein | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | All-trans-xanthophyll | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | Bo-xan | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | E 161 | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | E 161b | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | E-161B(I) | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | Floraglo | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | Floraglo lutein | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | INS NO.161B(I) | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | INS-161B(I) | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | Leutein | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | Lutein a | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | Lutein from tagetes erecta | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | NSC-59193 | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | Oro glo 7 | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | Os 24 | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | Trans-lutein | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | Vegetable lutein | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | Vegetable luteol | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | Xanthophyll | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Known as | Xantofyl | ChEMBL registry synonym — accepted as the source's own label CHEMBL173929 ↗ |
| Modality | Other / unclassified | “dietary supplement” NCT00449917 ↗ |
| Route | Oral | “varying doses of oral supplementation of lutein” NCT00006202 ↗ |