Drugs / YTTRIUM Y 90 CLIVATUZUMAB TETRAXETAN
YTTRIUM Y 90 CLIVATUZUMAB TETRAXETAN
also known as
90Y-hPAM4 · IMMU-107 · 90HY-PAM4 · 90Y-HPAMA4 · HPAM-4-DOTA · HPAM-DOTA HY-PAM4 · Hpam4-cide · Pan-cide · +3 more
Monoclonal antibody targets MUC1, MUC5AC
Trials 4
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 11 trial | ||||||
| Phase 1 | NCT01510561 | Mar 2012 → Jun 2015 | pancreatic adenocarcinoma | Gilead Sciences | Withdrawn | No outcome recorded Stop: Enrollment |
| Phase 1/22 trials | ||||||
| Phase 1/2 | NCT00603863 | Jan 2008 → Jul 2013 | malignant pancreatic neoplasm | Gilead Sciences | Completed | No outcome recorded |
| Phase 1/2 | NCT00597129 | Aug 2004 → Oct 2007 | malignant pancreatic neoplasm | Gilead Sciences | Completed | No outcome recorded |
| Phase 31 trial | ||||||
| Phase 3 | NCT01956812 | Dec 2013 → Nov 2016 | malignant pancreatic neoplasm | Gilead Sciences | Terminated | No outcome recorded |
Evidence & citations 16 cited values
Every value below carries the sentence it was read from. 5 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | YTTRIUM Y 90 CLIVATUZUMAB TETRAXETAN | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108708 ↗ |
| Known as | 90HY-PAM4 | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108708 ↗ |
| Known as | 90Y-hPAM4 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00597129 ↗ |
| Known as | 90Y-HPAMA4 | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108708 ↗ |
| Known as | HPAM-4-DOTA | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108708 ↗ |
| Known as | HPAM-DOTA HY-PAM4 | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108708 ↗ |
| Known as | Hpam4-cide | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108708 ↗ |
| Known as | IMMU-107 | ClinicalTrials.gov intervention name — accepted as the source's own label NCT00603863 ↗ |
| Known as | Pan-cide | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108708 ↗ |
| Known as | S9S0HY-PAM4 | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108708 ↗ |
| Known as | Ytrio (90y) clivatuzumab tetraxetan | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108708 ↗ |
| Known as | Yttrium (90y) clivatuzumab tetraxetan | ChEMBL registry synonym — accepted as the source's own label CHEMBL2108708 ↗ |
| Modality | Monoclonal antibody | — CHEMBL2108708 ↗ |
| Route | Intravenous | “administered intravenously as a single dose” NCT00597129 ↗ |
| Target | MUC1 | “radiolabeled anti-MUC1 humanized antibody” NCT00597129 ↗ |
| Target | MUC5AC | “Mucin-5AC binding agent” CHEMBL2108708 ↗ |