Drugs / SCB-2019

Trials 8 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 11 trial
Phase 1 NCT04932824 Jan → Nov 2021 COVID-19 Clover Biopharmaceuticals AUS Pty Completed No outcome recorded
Phase 22 trials
Phase 2 NCT05087368 Dec 2021 → Apr 2022 COVID-19 D'Or Institute for Research and Education Unknown No outcome recorded
Phase 2 NCT04954131 Aug → Nov 2021 COVID-19 Zhejiang Clover Biopharmaceuticals, Inc. Unknown No outcome recorded
Phase 2/32 trials
Phase 2/3 NCT05193279 Oct → Dec 2022 COVID-19 Clover Biopharmaceuticals AUS Pty Withdrawn No outcome recorded
Phase 2/3 NCT04672395 Mar 2021 → Sep 2022 COVID-19 Clover Biopharmaceuticals AUS Pty Completed No outcome recorded
Phase 33 trials
Phase 3 NCT05812586 Mar → Jun 2023 COVID-19 D'Or Institute for Research and Education Unknown No outcome recorded
Phase 3 NCT05188677 Jun 2022 → Jun 2023 COVID-19 Clover Biopharmaceuticals AUS Pty Completed No outcome recorded
Phase 3 NCT05012787 Nov 2021 → Mar 2022 COVID-19 Clover Biopharmaceuticals AUS Pty Terminated No outcome recorded
Also used as a comparator or background therapy in 4 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT05228314 Comparator May → Sep 2022 COVID-19 Clover Biopharmaceuticals AUS Pty Completed No outcome recorded
Phase 1 NCT04405908 Comparator Jun 2020 → Oct 2021 COVID-19 Clover Biopharmaceuticals AUS Pty Completed No outcome recorded
Phase 32 trials
Phase 3 NCT06567457 Comparator Oct 2023 → Sep 2024 COVID-19 Clover Biopharmaceuticals AUS Pty Withdrawn No outcome recorded
Phase 3 NCT05926440 Comparator Aug 2023 COVID-19 Clover Biopharmaceuticals AUS Pty Withdrawn No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 13 sources stand behind the page.

FieldValueCited text
Known as SCB 2019 “This study is to evaluate the safety and immunogenicity of the investigational CpG 1018/Alum-adjuvanted recombinant SARS-CoV-2 trimeric S-protein subunit vaccine (SCB 2019)...” NCT05012787
12

NCT05193279

NCT06567457

NCT05087368

NCT04954131

NCT04672395

NCT05012787

NCT04405908

NCT05228314

NCT05812586

NCT05188677

NCT05926440

NCT04932824

Known as S-Trimer “Safety and immunogenicity of S-Trimer (SCB-2019), a protein subunit vaccine candidate for COVID-19 in healthy adults: a phase 1, randomised, double-blind, placebo-controlled trial.” PMID 33524311 Jan 2021
Modality Vaccine “a protein subunit vaccine candidate for COVID-19” PMID 33524311 Jan 2021
Route Intramuscular “SCB-2019 intramuscular vaccinations at 3 µg up to 30 µg twice (on Day 1 and Day 22).” NCT04405908