drugset / Trial / NCT05228314

Safety and Immunogenicity Dose-finding Study of Adjuvanted SCB-2020S Vaccine in Adults

NCT05228314

Phase 1 Completed 153 enrolled Clover Biopharmaceuticals AUS Pty
RandomizedParallel-groupQuadruple-blindPrevention

Summary

This is a phase 1 study to assess the safety and immunogenicity of different formulations of the investigational adjuvanted recombinant SARS-CoV-2 trimeric S-protein (from beta variant) subunit vaccine (SCB-2020S vaccine), when administered as 2 dose vaccination series 21 days apart to adults ≥18 to ≤75 years of age.

Timeline

Start
2022-05-30
Primary completion
2022-09-23
Completion
2023-04-23

Drugs

EvaluationDrugModalityDoseRoute
Comparator SCB-2019 Vaccine
Subject SCB-2020S Vaccine

Indications