Drugs / Mo-Rez
last change Apr 2026 re-read 9 days ago

Mo-Rez

also known as Mocertatug Rezetecan
Developed for
female reproductive system neoplasm
Investigated by
GlaxoSmithKline

Trials 1

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 1/2 NCT06796907 Mar 2025 → Jun 2027 expected female reproductive system neoplasm GlaxoSmithKline Recruiting No outcome recorded

News releases announcing trial results or a regulatory action · 3

DateIssuerRelease
2026-04-12 GlaxoSmithKline Results GSK presents positive data for B7-H4-targeted ADC in gynaecological cancers gsk.com ↗
GSK plc (LSE/NYSE: GSK) today announced positive findings from its global phase I BEHOLD-1 clinical trial for mocertatug rezetecan (or Mo-Rez for short), a novel antibody-drug conjugate (ADC) targeting the B7-H4 antigen.
2026-03-02 Hansoh BioMedical R&D Company Results ESGO 2026 | 翰森制药Mocertatug Rezetecan(B7-H4 ADC)治疗铂敏感复发卵巢癌研究数据发布,其中一项研究入选LBA hansoh.cn ↗
Mocertatug rezetecan作为单药治疗及与贝伐珠单抗联合用药,在重度经治的铂敏感复发卵巢癌(PSOC)患者中显示出抗肿瘤活性,安全性可控.
2026-02-28 Jiangsu Hansoh Pharmaceutical Co., Ltd. Results ESGO 2026 | HANSOH PHARMA PRESENTED DATA FOR MOCERTATUG REZETECAN (HS-20089,A B7-H4-TARGETED ADC) IN PATIENTS WITH PLATINUM-SENSITIVE OVARIAN CANCER,WITH ONE STUDY SELECTED AS LBA hspharm.com ↗
Across the two studies, mocertatug rezetecan showed anti-tumor activity with a safety profile consistent with previous studies.

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 1 source stands behind the page.

FieldValueCited text
Known as Mo-Rez ClinicalTrials.gov intervention name — accepted as the source's own label NCT06796907 ↗
Known as Mocertatug Rezetecan “This study is looking at how safe and tolerable Mocertatug Rezetecan (Mo-Rez) is, how the body handles it, and how well it works when used with other cancer medicines.” NCT06796907 ↗
Route Intravenous “Mo-Rez will be administered intravenously (IV).” NCT06796907 ↗