Drugs / Prostaglandin E1
last change Jan 2026 re-read 3 minutes ago

Prostaglandin E1

also known as IPGE1 · PGE1
Developed for
erectile dysfunction · thrombotic disease · respiratory failure
Investigated by
Memorial Sloan Kettering Cancer Center · National Taiwan University Hospital · Pfizer

Trials 2

20082009201020112012201320142015201620172018201920202021202220232024202520262027
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 41 trial
Phase 4 NCT00733434 Jul 2008 → Jul 2009 thrombotic disease National Taiwan University Hospital Unknown No outcome recorded
Phase not applicable1 trial
— NCT00955929 Aug 2009 → Dec 2020 erectile dysfunction, penile cancer Memorial Sloan Kettering Cancer Center Terminated No outcome recorded Stop: Enrollment
Comparator or background therapy3 trials
Phase 2 NCT01108120 Comparator May 2010 → Dec 2022 ulcer of lower limbs Xiang Guang-da Completed Met primary
Phase 2 NCT00598429 Comparator May → Sep 2008 group B streptococcal infection, newborn respiratory distress syndrome, pulmonary hypertension, neonatal NICHD Neonatal Research Network Withdrawn No outcome recorded Stop: Enrollment
Phase 4 NCT07503184 Background Jul 2025 → Jan 2026 preterm premature rupture of the membranes Nishtar Medical University Completed No outcome recorded

Evidence & citations 4 cited values

Every value below carries the sentence it was read from. 6 sources stand behind the page.

FieldValueCited text
Known as Prostaglandin E1 “intravenous injection of prostaglandin E1 20 ug per day during hospitalization period” NCT01108120 ↗
4

NCT00733434 ↗

NCT00955929 ↗

NCT07503184 ↗

NCT00598429 ↗

Known as IPGE1 “The objective of this study was to evaluate the feasibility of a randomized controlled trial (RCT) of inhaled PGE1 (IPGE1) in NHRF.” PMID 25496504 ↗ Dec 2014
Known as PGE1 “intravenous form of Prostaglandin E1 (PGE1)” NCT00598429 ↗
Route Inhaled “using the intravenous form of Prostaglandin E1 in an inhaled form” NCT00598429 ↗