drugset / Trial / NCT07842120

Comparing MOP, Prostaglandin E1, and Calcitriol to Accelerate Orthodontic Tooth Movement

NCT07842120 ↗

Phase 2 Recruiting 60 enrolled Ghufran Dhari Awad
RandomizedParallel-groupTriple-blindTreatment

Summary

This study will compare the effects of MOP (micro-osteoperforation), prostaglandin E1, and calcitriol on the rate of orthodontic tooth movement. The study will evaluate whether these interventions can accelerate tooth movement during orthodontic treatment. The findings may help researchers better understand methods for making orthodontic treatment more efficient while evaluating the effects and safety of the interventions used in the study.

Timeline

Start
2026-04-16
Primary completion
2026-12-30
Completion
2027-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Calcitriol Small molecule 0.06 ng Other
Subject Prostaglandin E1 Unknown 60 ug Other

Indications

No indication recorded.