Drugs / AHB-137
last change Aug 2026 re-read 2 minutes ago

AHB-137

Antisense oligonucleotide

Developed for
chronic hepatitis B virus infection
Investigated by
Ausper Biopharma Co., Ltd. · AusperBio Therapeutics Inc.

Trials 12 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT07600788 May 2026 → May 2028 expected chronic hepatitis B virus infection Ausper Biopharma Co., Ltd. Not yet recruiting No outcome recorded
Phase 1 NCT05717686 Feb 2023 → Jan 2025 chronic hepatitis B virus infection AusperBio Therapeutics Inc. Completed No outcome recorded
Phase 1/21 trial
Phase 1/2 NCT06115993 Aug 2023 → Dec 2024 chronic hepatitis B virus infection Ausper Biopharma Co., Ltd. Completed No outcome recorded
Phase 28 trials
Phase 2 NCT07635186 Jun 2026 → Jun 2027 expected chronic hepatitis B virus infection Ausper Biopharma Co., Ltd. Not yet recruiting No outcome recorded
Phase 2 NCT07654283 Jun 2026 → Mar 2027 expected chronic hepatitis B virus infection AusperBio Therapeutics Inc. Not yet recruiting No outcome recorded
Phase 2 NCT07370207 Mar 2026 → Dec 2028 expected chronic hepatitis B virus infection AusperBio Therapeutics Inc. Recruiting No outcome recorded
Phase 2 NCT07137910 Sep 2025 → Dec 2026 expected chronic hepatitis B virus infection Ausper Biopharma Co., Ltd. Recruiting No outcome recorded
Phase 2 NCT06993480 Jul 2025 → Jul 2026 overdue chronic hepatitis B virus infection Ausper Biopharma Co., Ltd. Active not recruiting No outcome recorded
Phase 2 NCT07069569 Jun 2025 → Jul 2027 expected chronic hepatitis B virus infection Ausper Biopharma Co., Ltd. Recruiting No outcome recorded
Phase 2 NCT06829329 Dec 2024 → Aug 2026 overdue chronic hepatitis B virus infection Ausper Biopharma Co., Ltd. Active not recruiting No outcome recorded
Phase 2 NCT06550128 Jul 2024 → May 2025 overdue chronic hepatitis B virus infection Ausper Biopharma Co., Ltd. Active not recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT07246889 Aug 2025 → Dec 2026 expected chronic hepatitis B virus infection Ausper Biopharma Co., Ltd. Active not recruiting No outcome recorded

Evidence & citations 3 cited values

Every value below carries the sentence it was read from. 13 sources stand behind the page.

FieldValueCited text
Known as AHB-137 ClinicalTrials.gov intervention name — accepted as the source's own label NCT07654283
11

NCT05717686

NCT07635186

NCT06829329

NCT06115993

NCT07137910

NCT07246889

NCT06993480

NCT07600788

NCT07069569

NCT07370207

NCT06550128

Modality Antisense oligonucleotide “AHB-137 is a novel antisense oligonucleotide targeting a conserved 3'-terminal region of HBV mRNA.” PMID 42176239 May 2026
Route Subcutaneous “by subcutaneous (SC) injection” NCT05717686