drugset / Trial / NCT07246889

Study of AHB-137 in Participants With Chronic Hepatitis B (CHB) Treated With Nucleos(t)Ide Analogues (NAs)(AUSHINE)

NCT07246889

Phase 3 Active not recruiting 577 enrolled Ausper Biopharma Co., Ltd.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study is a randomized, double-blind, multicenter phase 3 clinical trial to evaluate the efficacy and safety of AHB-137 injection in participants with HBeAg-negative CHB treated with NAs.

Timeline

Start
2025-08-12
Primary completion
2026-12-18
Completion
2027-10-31

Drugs

EvaluationDrugModalityDoseRoute
Subject AHB-137 Antisense oligonucleotide Subcutaneous