Drugs / Vusolimogene Oderparepvec

Trials 9 · a red edge is where a trial was stopped

PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 01 trial
Phase 0 NCT06216938 Mar 2024 → Mar 2028 expected melanoma Yana Najjar Recruiting No outcome recorded
Phase 1/23 trials
Phase 1/2 NCT06067061 Apr 2024 → May 2025 triple-negative breast carcinoma Institut Curie Terminated No outcome recorded
Phase 1/2 NCT05858229 Jun 2023 → Dec 2025 overdue skin squamous cell carcinoma Sherrif Ibrahim Active not recruiting No outcome recorded
Phase 1/2 NCT04349436 May 2020 → Jul 2029 expected basal cell carcinoma, cutaneous neuroendocrine carcinoma, skin squamous cell carcinoma Replimune, Inc. Active not recruiting No outcome recorded
Phase 23 trials
Phase 2 NCT06898970 Jan 2026 → Oct 2029 expected angiosarcoma Varun Monga, MBBS Active not recruiting No outcome recorded
Phase 2 NCT04050436 Oct 2019 → Sep 2025 overdue skin squamous cell carcinoma Replimune, Inc. Active not recruiting No outcome recorded
Phase 2 NCT03767348 Sep 2017 → Jun 2028 expected cutaneous melanoma, non-small cell lung carcinoma, skin carcinoma Replimune, Inc. Active not recruiting No outcome recorded
Phase 31 trial
Phase 3 NCT06264180 Jul 2024 → Sep 2030 expected melanoma Replimune, Inc. Recruiting No outcome recorded
Phase not stated1 trial
NCT06590480 melanoma Replimune, Inc. No longer available No outcome recorded

Evidence & citations 6 cited values

Every value below carries the sentence it was read from. 11 sources stand behind the page.

FieldValueCited text
Known as vusolimogene oderparepvec “RP1 (vusolimogene oderparepvec) is a herpes simplex virus type 1-based oncolytic immunotherapy” PMID 40627813 Jul 2025
4

Vusolimogene OderparepvecNCT06067061

NCT06898970

NCT06264180

NCT06216938

Known as Hsv-1 oncolytic viral strain rp1 ChEMBL registry synonym — accepted as the source's own label CHEMBL4650271
Known as Immulytic “Atezolizumab plus RP1 (Immulytic™) oncolytic immunotherapy” NCT06067061
Known as Oncolytic virus rp1 ChEMBL registry synonym — accepted as the source's own label CHEMBL4650271
Known as RP1 “Vusolimogene oderparepvec (RP1)” NCT06216938
6

NCT06067061

NCT05858229

NCT03767348

NCT06590480

NCT04050436

NCT04349436

Route Other “RP1 was administered intratumorally” PMID 40627813 Jul 2025