drugset / Trial / NCT04050436

Study Evaluating Cemiplimab Alone and Combined With RP1 in Treating Advanced Squamous Skin Cancer

NCT04050436

Phase 2 Active not recruiting 231 enrolled Replimune, Inc. Regeneron Pharmaceuticals · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

To estimate the clinical benefit of cemiplimab monotherapy versus cemiplimab in combination with RP1 for patients with locally advanced or metastatic CSCC, as assessed by overall response rate (ORR) and complete response rate (CRR) according to blinded independent review.

Timeline

Start
2019-10-08
Primary completion
2025-09
Completion
2025-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Cemiplimab Monoclonal antibody Intravenous
Subject Vusolimogene Oderparepvec Unknown Other