Drugs / Trimethobenzamide
Trimethobenzamide
Regulatory milestones approvals, filings & regulatory actions · 2 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Label expansion | US (FDA) | TIGAN | — | 2001-12-13 | fda.gov ↗ |
| Approved | US (FDA) | TIGAN | — | 1974-07-12 | fda.gov ↗ |
Trials 2 · a red edge is where a trial was stopped
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 4 | NCT07681076 | Aug → Nov 2026 expected | — | Karuna Therapeutics, Inc. | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT00489255 | May 2007 → Dec 2011 | Parkinson disease | Ipsen | Completed | No outcome recorded |
Also used as a comparator or background therapy in 3 trials
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 12 trials | ||||||
| Phase 1 | NCT02373072 Background | Mar 2015 → Feb 2016 | Parkinson disease | Pfizer | Completed | No outcome recorded |
| Phase 1 | NCT02262767 Background | Nov → Dec 2014 | — | Pfizer | Completed | No outcome recorded |
| Phase 41 trial | ||||||
| Phase 4 | NCT01770145 Background | Dec 2012 → Apr 2014 | Parkinson disease, akinetopsia, movement disorder | Supernus Pharmaceuticals | Completed | No outcome recorded |
Evidence & citations 10 cited values
Every value below carries the sentence it was read from. 6 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Trimethobenzamide | “Tigan® (trimethobenzamide) in preventing nausea and vomiting when initiating therapy with Apokyn® (apomorphine)” NCT00489255 ↗ |
| Known as | Ametik damla | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201256 ↗ |
| Known as | NSC-37882 | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201256 ↗ |
| Known as | Tigan | “Tigan® (trimethobenzamide) in preventing nausea and vomiting when initiating therapy with Apokyn® (apomorphine)” NCT00489255 ↗ |
| Known as | Trimethobenzamide hcl | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201256 ↗ |
| Known as | Trimethobenzamide Hydrochloride | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02373072 ↗ |
| Known as | Trimethobenzamide hydrochloride preservative free | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201256 ↗ |
| Known as | Trimetobenzamida | ChEMBL registry synonym — accepted as the source's own label CHEMBL1201256 ↗ |
| Modality | Small molecule | — CHEMBL1201256 ↗ |
| Route | Oral | “Oral capsule, 300mg three times daily” NCT00489255 ↗ |