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Drugs / Lactobacillus plantarum 299v

Follow last change Aug 2026 re-read 2 minutes ago

Lactobacillus plantarum 299v

also known as L. plantarum 299v · Lactobacillus plantarum strain 299v · LP299V

Other / unclassified

Developed for: irritable bowel syndrome · acute graft versus host disease · diabetic macular edema · major depressive disorder
Investigated by: Children's Oncology Group · EP Plus Group Sdn Bhd · Massachusetts Eye and Ear Infirmary · National Cancer Institute (NCI) · National Research Foundation (NRF) (RSA) · Nestlè Nutrition Institute Africa
+1 more
· University of Stellenbosch

Trials 4 · a red edge is where a trial was stopped

today NCT07383701 · Ph 2 NCT06271538 · Ph 4 NCT03057054 · Ph 3 NCT01886781 · Ph 4

20112012201320142015201620172018201920202021202220232024202520262027

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 21 trial
Phase 2	NCT07383701	Aug 2026 → Mar 2027 expected	diabetic macular edema	Massachusetts Eye and Ear Infirmary	Not yet recruiting	No outcome recorded
Phase 31 trial
Phase 3	NCT03057054	Apr 2018 → Jun 2022 overdue	acute graft versus host disease, leukemia, lymphoma	Children's Oncology Group	Active not recruiting	No outcome recorded
Phase 42 trials
Phase 4	NCT06271538	Oct 2024 → Mar 2026 overdue	functional colonic disease, irritable bowel syndrome	EP Plus Group Sdn Bhd	Recruiting	No outcome recorded
Phase 4	NCT01886781	Jan 2011 → Jun 2013	irritable bowel syndrome	University of Stellenbosch	Completed	No outcome recorded

Also used as a comparator or background therapy in 1 trial

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 2	NCT02469545 Comparator	Jun 2014 → Mar 2016	anxiety disorder, major depressive disorder	Medical University of Bialystok	Completed	No outcome recorded

Evidence & citations 7 cited values

Every value below carries the sentence it was read from. 5 sources stand behind the page.

Field	Value	Cited text
Known as	Lactobacillus plantarum 299v	“This study seeks to provide efficacy insights into Skal Pro powder 2g (containing Lactobacillus plantarum 299v 1x10\^10 colony forming unit (CFU) and GOS), shedding light on...” NCT06271538 ↗ 3 NCT02469545 ↗ NCT07383701 ↗ NCT01886781 ↗
Known as	L. plantarum 299v	“Oral probiotic supplement L. plantarum 299v twice daily for 4 months for both groups.” NCT07383701 ↗
Known as	Lactobacillus plantarum strain 299v	ClinicalTrials.gov intervention name — accepted as the source's own label NCT03057054 ↗
Known as	LP299V	“Skal Pro in the form of 2g sachet powder contains 10 billion CFU of freeze-dried Lactobacillus plantarum 299v (LP299V) and galactooligosaccharides (GOS).” NCT06271538 ↗
Modality	Other / unclassified	“the effect of a probiotic, Lactobacillus plantarum 299v” NCT01886781 ↗
Route	Oral	“Patients receive Lactobacillus plantarum strains 299 and 299v orally (PO) or through nasojejunal (NJ), nasogastric (NG) or gastronomy (G) tube once daily (QD) on day 1 of...” NCT03057054 ↗
Route	Other	“Patients receive Lactobacillus plantarum strains 299 and 299v orally (PO) or through nasojejunal (NJ), nasogastric (NG) or gastronomy (G) tube once daily (QD) on day 1 of...” NCT03057054 ↗