drugset / Trial / NCT02469545
Effect of Lactobacillus Plantarum 299v Supplementation on Major Depression Treatment
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The aim of the study is to determine the influence of supplementation of probiotic Lactobacillus Plantarum 299V vs. placebo of probiotic during antidepressant monotherapy with SSRI (Selective Serotonin Reuptake Inhibitor) in patients with major depression.
Timeline
- Start
- 2014-06
- Primary completion
- 2016-03
- Completion
- 2016-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Lactobacillus plantarum 299v | Other / unclassified | 1e+10 cells | — |
| Comparator | Escitalopram | Small molecule | 5 mg | — |
| Comparator | Escitalopram | Small molecule | 20 mg | — |
| Comparator | Sertraline | Small molecule | 50 mg | — |
| Comparator | Sertraline | Small molecule | 100 mg | — |