Escitalopram

also known as Lexapro · escitalopram oxalate · cipralex · ESC · escitalopram (Lexapro) · s-CIT · Lexapro (escitalopram) · S-citalopram · +5 more

Small molecule targets CYP2D6 via inhibition

Developed for: major depressive disorder · depressive disorder · anxiety · dysthymic disorder · obsessive-compulsive disorder · generalized anxiety disorder · schizophrenia · anxiety disorder
+61 more
· post-traumatic stress disorder · Alzheimer disease · stroke disorder · bipolar disorder · coronary artery disorder · dementia · epilepsy · irritable bowel syndrome · postpartum depression · bipolar depression · borderline personality disorder · eating disorder · insomnia · ischemic stroke · multiple sclerosis · somatoform disorder · spinal cord injury · type 2 diabetes mellitus · alcohol dependence · aphasia · atypical depressive disorder · autism spectrum disorder · bipolar I disorder · bipolar II disorder · brain glioma · chronic obstructive pulmonary disease · chronic pain syndrome · cocaine dependence · cognitive impairment with or without cerebellar ataxia · dyspepsia · fibromyalgia · impulse control disorder · mental disorder · myocardial ischemia · overactive bladder · panic disorder · phobic disorder · polyneuropathy · premature ejaculation · premenstrual tension · rheumatoid arthritis · sleep disorder · social phobia · substance dependence · agoraphobia · asthma · burning mouth syndrome · cancer · cannabis dependence · chronic rhinosinusitis · cocaine abuse · end stage renal failure · melancholia · metastatic neoplasm · mixed anxiety and depressive disorder · neurological pain disorder · polycystic ovary syndrome · premature menopause · psychotic disorder · pulmonary hypertension · separation anxiety disorder
Investigated by: Forest Laboratories · National Institute of Mental Health (NIMH) · H. Lundbeck A/S · Massachusetts General Hospital · New York State Psychiatric Institute · Duke University
+229 more
· University of Pennsylvania · Weill Medical College of Cornell University · University of Pittsburgh · Emory University · Otsuka Pharmaceutical Development & Commercialization, Inc. · Seoul National University Hospital · Indiana University · Peking University · Sheba Medical Center · BeerYaakov Mental Health Center · Eli Lilly and Company · Hoffmann-La Roche · Lundbeck Israel · Medical University of Vienna · Rigshospitalet, Denmark · Samsung Medical Center · Shirley Ryan AbilityLab · University of Cincinnati · Xian-Janssen Pharmaceutical Ltd. · AstraZeneca · Cairo University · Centre for Addiction and Mental Health · Dr. Inge Winter · First Hospital of China Medical University · GlaxoSmithKline · Hadassah Medical Organization · Johns Hopkins University · Lundbeck Foundation · Max-Planck-Institute of Psychiatry · Mayo Clinic · Mylan Pharmaceuticals Inc · National Heart, Lung, and Blood Institute (NHLBI) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Nova Scotia Health Authority · Oregon Health and Science University · Seoul National University Bundang Hospital · Shanghai Mental Health Center · Stanford University · The First Hospital of Hebei Medical University · University Health Network, Toronto · University of Cambridge · University of Minnesota · University of Münster · University of Nebraska · University of Ottawa · University of Rochester · University of Sao Paulo · University of South Carolina · University of Southern Denmark · Wake Forest University Health Sciences · Washington University School of Medicine · Aarhus University Hospital · Abarbanel Mental Health Center · AbbVie · Academy of Finland · Ajay Wasan, MD, Msc · All India Institute of Medical Sciences, Bhopal · Amager Hospital · Amsterdam UMC, location VUmc · Asan Medical Center · Augusta University · Azienda Ospedaliero Universitaria Maggiore della Carita · BC Women's Hospital & Health Centre · Beitou Armed Forces Hospital, Taipei, Taiwan · Bispebjerg Hospital · Brigham and Women's Hospital · Bristol-Myers Squibb · Bronx VA Medical Center · Burke Medical Research Institute · Cantonal Hospital of St. Gallen · Capital Medical University · Case Comprehensive Cancer Center · Cedars-Sinai Medical Center · Center for Integrated Molecular Brain Imaging, Copenhagen, Denmak · all 235 on the full record

Regulatory milestones approvals, filings & regulatory actions · 4 recorded

Milestone	Jurisdiction	Brand	Indication	Date	Sentence it was read from
Label expansions (3)	US (FDA)	LEXAPRO	—	2003-12-18 – 2023-05-12	fda.gov ↗
Approved	US (FDA)	LEXAPRO	—	2002-08-14	fda.gov ↗

Trials 244 · started per year

today

US approved 2002

2001200220032004200520062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 03 trials
Phase 0	NCT06796946	Jun → Dec 2026 expected	—	University of Huelva	Not yet recruiting	No outcome recorded
Phase 0	NCT03623711	Aug 2018 → Dec 2022	major depressive disorder	Yuqi Cheng	Unknown	No outcome recorded
Phase 0	NCT00656552	May → Dec 2008	premature ejaculation	Cairo University	Unknown	No outcome recorded
Phase 123 trials · 1 met primary
Phase 1	NCT07139834	Jun 2026 → Jun 2027 expected	major depressive disorder	Jeffrey Miller	Recruiting	No outcome recorded
Phase 1	NCT06680531	Aug → Sep 2024	insomnia	Shanghai Haiyan Pharmaceutical Technology Co., Ltd.	Completed	No outcome recorded
Phase 1	NCT04836533	Jan 2023	depressive disorder	Queens College, The City University of New York	Withdrawn	No outcome recorded
Phase 1	NCT05470465	Sep 2022 → Sep 2023	respiratory underresponsiveness to hypoxia and hypercapnia	Food and Drug Administration (FDA)	Completed	Met primary
Phase 1	NCT02869035	Aug 2016 → Jul 2019	major depressive disorder	Rigshospitalet, Denmark	Completed	No outcome recorded
Phase 1	NCT02175602	Jun → Aug 2014	hepatitis C virus infection	Bristol-Myers Squibb	Completed	No outcome recorded
Phase 1	NCT02122939	Sep 2013 → Mar 2014	—	Seoul National University Hospital	Completed	No outcome recorded
Phase 1	NCT01871701	Nov 2012 → May 2014	—	Seoul National University Hospital	Completed	No outcome recorded
Phase 1	NCT01753882	Feb 2012 → Jul 2020	spinal cord injury	Shirley Ryan AbilityLab	Unknown	No outcome recorded
Phase 1	NCT01418274	Aug → Sep 2011	—	Hoffmann-La Roche	Completed	No outcome recorded
Phase 1	NCT01638689	Sep 2010 → Feb 2011	—	Karolinska Institutet	Completed	No outcome recorded
Phase 1	NCT01090700	May → Sep 2010	chronic hepatitis C virus infection	Tibotec Pharmaceuticals, Ireland	Completed	No outcome recorded
Phase 1	NCT01045083	Jan 2010 → Jun 2011	—	Hoffmann-La Roche	Completed	No outcome recorded
Phase 1	NCT00933894	Sep → Nov 2009	chronic hepatitis C virus infection	Tibotec BVBA	Completed	No outcome recorded
Phase 1	NCT00787501	Jun 2008 → Jul 2011	major depressive disorder	University of Pittsburgh	Completed	No outcome recorded
Phase 1	NCT01293838	Mar 2008 → Jan 2012	anxiety disorder	University of Ottawa	Unknown	No outcome recorded
Phase 1	NCT00414323	Nov 2006 → May 2007	major depressive disorder	Eli Lilly and Company	Completed	No outcome recorded
Phase 1	NCT00361790	Aug → Nov 2006	—	Otsuka Pharmaceutical Development & Commercialization, Inc.	Completed	No outcome recorded
Phase 1	NCT01788969	Jun 2005 → Dec 2016	spinal cord injury	Shirley Ryan AbilityLab	Unknown	No outcome recorded
Phase 1	NCT00613470	Mar 2005 → May 2013	depressive disorder	Mayo Clinic	Completed	No outcome recorded
Phase 1	NCT01751854	Dec 2004 → Jan 2012	—	Shirley Ryan AbilityLab	Completed	No outcome recorded
Phase 1	NCT00648661	Sep → Oct 2004	—	Mylan Pharmaceuticals Inc	Completed	No outcome recorded
Phase 1	NCT00648570	Aug → Oct 2004	—	Mylan Pharmaceuticals Inc	Completed	No outcome recorded

Phase 1/22 trials
Phase 1/2	NCT06696482	Jan → Sep 2025 overdue	—	University of Oxford	Not yet recruiting	No outcome recorded
Phase 1/2	NCT04221256	Mar 2020 → Feb 2021	ischemic stroke	Burke Medical Research Institute	Withdrawn	No outcome recorded
Phase 225 trials · 2 met primary · 6 missed
Phase 2	NCT06705478	May → Dec 2026	HIV infectious disease, cognitive disorder, major depressive disorder	National Institute of Allergy and Infectious Diseases (NIAID)	Suspended	No outcome recorded Stop: Enrollment
Phase 2	NCT06826326	Apr 2025 → Dec 2026 expected	autism spectrum disorder	Kathryn Unruh	Enrolling by invitation	No outcome recorded
Phase 2	NCT05536414	Sep 2022 → May 2025	major depressive disorder	Otsuka Pharmaceutical Development & Commercialization, Inc.	Completed	No outcome recorded
Phase 2	NCT05289830	Aug 2022 → Aug 2023	pancreatic ductal adenocarcinoma, periampullary adenocarcinoma	Case Comprehensive Cancer Center	Terminated	No outcome recorded Stop: Enrollment
Phase 2	NCT05002309	Dec 2021 → Jun 2028 expected	major depressive disorder	Nova Scotia Health Authority	Recruiting	No outcome recorded
Phase 2	NCT03843463	Jul 2021 → Feb 2027 expected	aphasia, stroke disorder	Johns Hopkins University	Recruiting	No outcome recorded
Phase 2	NCT04437485	Oct 2020 → Aug 2022	dysthymic disorder, major depressive disorder, prediabetes syndrome, type 2 diabetes mellitus	Indiana University	Completed	Missed primary
Phase 2	NCT03728673	Mar 2019 → Jun 2027 expected	brain glioma	University of Nebraska	Recruiting	No outcome recorded
Phase 2	NCT03222570	Feb 2018 → Apr 2024	depressive disorder	University of Minnesota	Completed	Missed primary
Phase 2	NCT03527043	Oct 2017 → Apr 2023	spermatogenic failure	Weill Medical College of Cornell University	Terminated	No outcome recorded Stop: Business
Phase 2	NCT02865642	Aug 2016 → Sep 2020	ischemic stroke	Insel Gruppe AG, University Hospital Bern	Unknown	No outcome recorded
Phase 2	NCT03010761	Jan 2016 → Jan 2018	substance dependence	China Medical University Hospital	Terminated	No outcome recorded
Phase 2	NCT02458690	Jul 2015 → Aug 2019	coronary artery disorder, dysthymic disorder, major depressive disorder, stroke disorder	Indiana University	Completed	Missed primary
Phase 2	NCT01103180	Sep 2010 → Nov 2014	borderline personality disorder	University of Chicago	Terminated	No outcome recorded Stop: Enrollment
Phase 2	NCT01368432	Apr 2010 → Dec 2012	major depressive disorder, traumatic brain injury	Johns Hopkins University	Completed	No outcome recorded
Phase 2	NCT01008098	Nov 2008 → Feb 2014	post-traumatic stress disorder	Seoul National University Hospital	Unknown	No outcome recorded
Phase 2	NCT00807248	Nov 2008 → Dec 2009	major depressive disorder	H. Lundbeck A/S	Completed	Missed primary
Phase 2	NCT00742573	Aug 2008 → Jan 2014	major depressive disorder	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 2	NCT00584571	Dec 2007 → Dec 2015	irritable bowel syndrome	Augusta University	Completed	Mixed
Phase 2	NCT00343070	Mar 2007 → Oct 2009	major depressive disorder	University Hospital, Ghent	Completed	No outcome recorded
Phase 2	NCT00166296	Mar 2005 → Oct 2007	chronic hepatitis C virus infection, major depressive disorder	Germans Trias i Pujol Hospital	Completed	Missed primary
Phase 2	NCT00215137	Oct 2004 → Jan 2009	obsessive-compulsive disorder	Duke University	Completed	Met primary
Phase 2	NCT00149825	Jun 2004 → Aug 2007	insomnia, major depressive disorder	Stanford University	Completed	Missed primary
Phase 2	NCT00086307	Jun 2004 → Mar 2010	major depressive disorder	National Institute of Mental Health (NIMH)	Completed	Met primary
Phase 2	NCT00156325	Feb 2004 → Feb 2005	bipolar II disorder	The University of New South Wales	Completed	No outcome recorded

Phase 2/312 trials
Phase 2/3	NCT05519683	Nov 2022 → Mar 2027 expected	irritable bowel syndrome	University of Michigan	Recruiting	No outcome recorded
Phase 2/3	NCT04747314	Mar 2021 → Nov 2024	anxiety, chronic pain syndrome	Ajay Wasan, MD, Msc	Completed	No outcome recorded
Phase 2/3	NCT03487211	Apr 2018 → Feb 2020	fibromyalgia	Shaheed Zulfiqar Ali Bhutto Medical University	Completed	No outcome recorded
Phase 2/3	NCT02623231	Dec 2015 → Dec 2017	depressive disorder, glioblastoma	Tel-Aviv Sourasky Medical Center	Unknown	No outcome recorded
Phase 2/3	NCT00866593	Mar 2009 → Mar 2010	depressive disorder	Shanghai Mental Health Center	Completed	No outcome recorded
Phase 2/3	NCT00767624	Dec 2008 → Jun 2015	major depressive disorder, sleep disorder, initiating and maintaining sleep	Stanford University	Completed	Mixed
Phase 2/3	NCT00732901	Jun 2008 → Feb 2013	cocaine dependence	Virginia Commonwealth University	Completed	No outcome recorded
Phase 2/3	NCT01876823	Apr 2006 → Mar 2010	Alzheimer disease, cognitive impairment with or without cerebellar ataxia, major depressive disorder	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 2/3	NCT00655057	Oct 2005 → Aug 2009	depressive disorder	University of Pennsylvania	Completed	No outcome recorded
Phase 2/3	NCT00215228	Jul 2005 → Aug 2007	major depressive disorder	Duke University	Completed	No outcome recorded
Phase 2/3	NCT00080158	Mar 2004 → Jun 2007	depressive disorder	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 2/3	NCT00121069	Sep 2002 → Sep 2004	phobic disorder	Connor, Kathryn M., M.D.	Completed	No outcome recorded

Phase 335 trials · 3 met primary · 3 missed
Phase 3	NCT05603104	Apr 2025 → Jun 2028 expected	bipolar depression, major depressive disorder, schizophrenia	Dr. Inge Winter	Recruiting	No outcome recorded
Phase 3	NCT05973786	Feb 2025 → Jun 2028 expected	bipolar depression	Dr. Inge Winter	Recruiting	No outcome recorded
Phase 3	NCT06153004	Aug 2023 → Mar 2024	depressive disorder	Harvard Medical School (HMS and HSDM)	Completed	No outcome recorded
Phase 3	NCT05480878	Dec 2022 → Mar 2023	rheumatoid arthritis	Tanta University	Completed	No outcome recorded
Phase 3	NCT05950061	Jun → Oct 2022	major depressive disorder	KRL Hospital, Islamabad	Completed	No outcome recorded
Phase 3	NCT02532660	Jul 2018 → Jun 2022	depressive disorder	Laboratório Catarinense SA	Terminated	No outcome recorded Stop: Enrollment
Phase 3	NCT03108846	Jan 2018 → Apr 2024 overdue	dementia	JHSPH Center for Clinical Trials	Active not recruiting	Missed primary
Phase 3	NCT02374567	Jan 2015 → Jun 2017	anxiety disorder, dementia, depressive disorder, schizophrenia +1	Hannover Medical School	Terminated	No outcome recorded
Phase 3	NCT02153567	Dec 2013 → Dec 2018	anxiety, depressive disorder, dyspepsia	Chinese University of Hong Kong	Completed	No outcome recorded
Phase 3	NCT00488670	Dec 2010 → Jun 2011	depressive disorder	University of British Columbia	Terminated	No outcome recorded
Phase 3	NCT01123707	Nov 2010 → Sep 2011	major depressive disorder	Otsuka Pharmaceutical Development & Commercialization, Inc.	Terminated	No outcome recorded Stop: Business
Phase 3	NCT01111565	Oct 2010 → Sep 2011	major depressive disorder	Otsuka Pharmaceutical Development & Commercialization, Inc.	Terminated	Missed primary Stop: Business
Phase 3	NCT01111539	Jul 2010 → Sep 2011	major depressive disorder	Otsuka Pharmaceutical Development & Commercialization, Inc.	Terminated	Missed primary Stop: Business
Phase 3	NCT01401595	Dec 2009 → Sep 2011	eating disorder	University of Pennsylvania	Completed	No outcome recorded
Phase 3	NCT00965497	Jul 2009 → Mar 2010	amyotrophic lateral sclerosis, major depressive disorder, multiple sclerosis	University of South Carolina	Completed	No outcome recorded
Phase 3	NCT00887679	May → Sep 2009	HIV infectious disease, anxiety disorder	Duke University	Completed	No outcome recorded
Phase 3	NCT02246244	Apr 2009 → Mar 2013	upper aerodigestive tract neoplasm	Gustave Roussy, Cancer Campus, Grand Paris	Completed	No outcome recorded
Phase 3	NCT00837564	Feb 2009 → Apr 2010	major depressive disorder	University Hospital Freiburg	Unknown	No outcome recorded
Phase 3	NCT00668525	Apr 2008 → Feb 2009	major depressive disorder	Forest Laboratories	Completed	No outcome recorded
Phase 3	NCT00351169	May 2006 → Jun 2007	major depressive disorder	AstraZeneca	Completed	No outcome recorded
Phase 3	NCT00329446	Apr 2006 → Sep 2007	generalized anxiety disorder	AstraZeneca	Completed	No outcome recorded
Phase 3	NCT00387348	Mar 2006 → Apr 2011	bile duct cancer, colorectal cancer, depressive disorder, esophageal cancer +3	Massachusetts General Hospital	Terminated	No outcome recorded
Phase 3	NCT00305500	Mar → Dec 2006	obsessive-compulsive disorder	Abarbanel Mental Health Center	Completed	No outcome recorded
Phase 3	NCT00296933	Dec 2005 → ?	major depressive disorder	University Health Network, Toronto	Completed	No outcome recorded
Phase 3	NCT00610506	Oct 2005 → May 2007	atypical depressive disorder	Duke University	Completed	No outcome recorded
Phase 3	NCT00361218	Oct 2005 → Dec 2008	major depressive disorder	Massachusetts General Hospital	Completed	No outcome recorded
Phase 3	NCT00114374	Jun 2005 → Jun 2007	anxiety disorder	Massachusetts General Hospital	Terminated	No outcome recorded
Phase 3	NCT00149799	May 2005 → Mar 2013	anxiety disorder, somatoform disorder	Massachusetts General Hospital	Completed	Met primary
Phase 3	NCT00108979	Mar 2005 → Jul 2006	major depressive disorder	Forest Laboratories	Completed	No outcome recorded
Phase 3	NCT00107120	Mar 2005 → May 2007	major depressive disorder	Forest Laboratories	Completed	Met primary
Phase 3	NCT00109044	Mar 2005 → May 2006	major depressive disorder	Forest Laboratories	Completed	No outcome recorded
Phase 3	NCT00239954	Mar 2005 → ?	major depressive disorder	Pharmacology Research Institute	Unknown	No outcome recorded
Phase 3	NCT00148447	Nov 2004 → Sep 2005	schizophrenia	BeerYaakov Mental Health Center	Completed	No outcome recorded
Phase 3	NCT00073411	Nov 2003 → May 2005	depressive disorder	Eli Lilly and Company	Completed	Met primary
Phase 3	NCT01522092	—	anxiety, chronic obstructive pulmonary disease	Hull University Teaching Hospitals NHS Trust	Withdrawn	No outcome recorded

Phase 4103 trials · 7 met primary · 7 missed
Phase 4	NCT07432815	Feb → Jun 2026	anxiety, depressive disorder, psoriasis	Cairo University	Completed	No outcome recorded
Phase 4	NCT07488910	Feb 2026 → Jan 2028 expected	major depressive disorder	Goethe University	Not yet recruiting	No outcome recorded
Phase 4	NCT06433635	Oct 2024 → Feb 2030 expected	bipolar I disorder, depressive disorder	Massachusetts General Hospital	Active not recruiting	No outcome recorded
Phase 4	NCT04623099	Mar 2021 → Jun 2026 overdue	anxiety	University of Cincinnati	Recruiting	No outcome recorded
Phase 4	NCT04697693	Mar → May 2021	major depressive disorder, post-traumatic stress disorder	New York State Psychiatric Institute	Terminated	No outcome recorded Stop: Enrollment
Phase 4	NCT04239339	Apr 2020 → Oct 2022	—	Rigshospitalet, Denmark	Completed	No outcome recorded
Phase 4	NCT04336228	Apr 2020 → Dec 2027 expected	obsessive-compulsive disorder	Rigshospitalet, Denmark	Active not recruiting	No outcome recorded
Phase 4	NCT05145270	Nov 2019 → Nov 2022	major depressive disorder	Shanghai Mental Health Center	Unknown	No outcome recorded
Phase 4	NCT03993457	Jul 2019 → Mar 2022	depressive disorder	University of Texas Southwestern Medical Center	Terminated	No outcome recorded
Phase 4	NCT03924323	May 2019 → Sep 2021	generalized anxiety disorder	AbbVie	Completed	Met primary
Phase 4	NCT03993535	Oct 2018 → Apr 2023	obsessive-compulsive disorder	University of Sao Paulo	Completed	No outcome recorded
Phase 4	NCT03464383	May 2018 → Sep 2019	anxiety, depressive disorder, epilepsy	Wake Forest University Health Sciences	Completed	No outcome recorded
Phase 4	NCT03522987	May 2018	anxiety, depressive disorder, epilepsy	Wake Forest University Health Sciences	Withdrawn	No outcome recorded
Phase 4	NCT04234776	Apr 2018 → Jun 2020	depressive disorder	University of Sao Paulo	Unknown	No outcome recorded
Phase 4	NCT03128021	May 2017 → Jun 2023	major depressive disorder	Howard Aizenstein	Completed	No outcome recorded
Phase 4	NCT03162185	Apr → Nov 2017	—	Max Planck Institute for Human Cognitive and Brain Sciences	Unknown	No outcome recorded
Phase 4	NCT02620150	Feb 2017 → Mar 2022	AIDS, depressive disorder	University of Pennsylvania	Completed	No outcome recorded
Phase 4	NCT02752542	Oct 2016 → Jun 2026 overdue	dysthymic disorder, major depressive disorder	Nova Scotia Health Authority	Recruiting	No outcome recorded
Phase 4	NCT02753738	Aug 2016 → Aug 2019	—	Medical University of Vienna	Unknown	No outcome recorded
Phase 4	NCT02711215	May 2015 → Jan 2020	major depressive disorder	Medical University of Vienna	Unknown	No outcome recorded
Phase 4	NCT02389465	Aug 2014 → Jul 2022	depressive disorder	University of Pennsylvania	Completed	No outcome recorded
Phase 4	NCT02161458	Jun 2014 → Aug 2017	—	University of Pennsylvania	Completed	Met primary
Phase 4	NCT01870843	Mar 2014 → May 2015	major depressive disorder	Xian-Janssen Pharmaceutical Ltd.	Completed	No outcome recorded
Phase 4	NCT01973283	Feb 2014 → Dec 2019	dysthymic disorder, major depressive disorder	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 4	NCT01916824	Aug 2013 → Dec 2015	major depressive disorder	Emory University	Completed	No outcome recorded
Phase 4	NCT01997580	Jul 2013 → Dec 2016	major depressive disorder	Seoul National University Bundang Hospital	Unknown	No outcome recorded
Phase 4	NCT01787240	Nov 2012 → Aug 2016	major depressive disorder	Massachusetts General Hospital	Terminated	No outcome recorded Stop: Enrollment
Phase 4	NCT01796132	Aug 2012 → Dec 2016	depressive disorder, lactation disease	Centre Hospitalier Universitaire Vaudois	Unknown	No outcome recorded
Phase 4	NCT01728194	Jul 2012 → Jul 2019	major depressive disorder	Weill Medical College of Cornell University	Completed	Met primary
Phase 4	NCT01628783	Jun 2012 → Dec 2014	depressive disorder	Jesper Ekelund	Unknown	No outcome recorded
Phase 4	NCT01594866	May 2012 → Jun 2016	major depressive disorder	Seoul National University Hospital	Completed	No outcome recorded
Phase 4	NCT01841125	Nov 2011 → Jul 2014	Alzheimer disease	Konkuk University Medical Center	Completed	No outcome recorded
Phase 4	NCT02237937	Sep 2011 → Dec 2014	major depressive disorder	HolsboerMaschmeyer NeuroChemie GmbH	Unknown	No outcome recorded
Phase 4	NCT01251471	Aug 2011 → Jul 2014	depressive disorder	Medical University of Vienna	Completed	No outcome recorded
Phase 4	NCT01278498	Jan 2011 → Dec 2014	depressive disorder	Asan Medical Center	Unknown	Missed primary
Phase 4	NCT01198795	Sep 2010 → Jan 2013	major depressive disorder	Forest Laboratories	Completed	No outcome recorded
Phase 4	NCT01078870	Feb 2010 → Jan 2011	schizophrenia	National Taiwan University Hospital	Unknown	No outcome recorded
Phase 4	NCT01814085	Feb 2010 → Feb 2012	major depressive disorder	Xian-Janssen Pharmaceutical Ltd.	Completed	No outcome recorded
Phase 4	NCT00974155	Sep 2009 → May 2014	major depressive disorder	K. Lieb	Completed	No outcome recorded
Phase 4	NCT00660062	Aug 2009 → Nov 2014	major depressive disorder	Hillerod Hospital, Denmark	Terminated	Missed primary
Phase 4	NCT01814098	Jul 2009 → May 2011	major depressive disorder	Xian-Janssen Pharmaceutical Ltd.	Completed	No outcome recorded
Phase 4	NCT00967408	Jul 2009 → Jul 2010	stroke disorder	Azienda Ospedaliero Universitaria Maggiore della Carita	Unknown	No outcome recorded
Phase 4	NCT00872027	Apr 2009 → Apr 2011	depressive disorder	University of Minnesota	Completed	No outcome recorded
Phase 4	NCT00902564	Mar → Dec 2009	generalized anxiety disorder	H. Lundbeck A/S	Completed	No outcome recorded
Phase 4	NCT00902226	Mar → Dec 2009	social phobia	H. Lundbeck A/S	Completed	No outcome recorded
Phase 4	NCT01541475	Mar 2009 → Jan 2011	major depressive disorder	Ewha Womans University	Completed	No outcome recorded
Phase 4	NCT00693732	Feb 2009 → Jan 2012	irritable bowel syndrome	National University Hospital, Singapore	Completed	No outcome recorded
Phase 4	NCT00833469	Jan 2009 → Apr 2011	postpartum depression	Massachusetts General Hospital	Completed	No outcome recorded
Phase 4	NCT00810069	Nov 2008 → Feb 2010	major depressive disorder	Eli Lilly and Company	Completed	Missed primary
Phase 4	NCT01398514	Oct 2008 → Jun 2011	—	Massachusetts General Hospital	Completed	No outcome recorded
Phase 4	NCT00785434	Oct 2008 → Dec 2009	major depressive disorder	Community Pharmacology Services Ltd	Completed	No outcome recorded
Phase 4	NCT00708396	Jul 2008 → Jul 2010	obsessive-compulsive disorder, schizophrenia	BeerYaakov Mental Health Center	Unknown	No outcome recorded
Phase 4	NCT00707863	May 2008 → Dec 2012	major depressive disorder	Indiana University	Completed	No outcome recorded
Phase 4	NCT00650897	Apr 2008 → Jun 2009	diabetes mellitus, major depressive disorder	Sheba Medical Center	Unknown	No outcome recorded
Phase 4	NCT00523705	Feb 2008 → Oct 2009	premenstrual tension	University of Pennsylvania	Terminated	Missed primary Stop: Enrollment
Phase 4	NCT00692263	Feb → Aug 2008	—	University of Southern Denmark	Completed	No outcome recorded
Phase 4	NCT00536172	Dec 2007 → Jun 2012	depressive disorder	University of Nebraska	Completed	Met primary
Phase 4	NCT00227292	Nov 2007 → Nov 2012	depressive disorder	Martin-Luther-University Halle-Wittenberg	Withdrawn	No outcome recorded
Phase 4	NCT01244724	Oct 2007 → Dec 2011	epilepsy, major depressive disorder	Weill Medical College of Cornell University	Terminated	No outcome recorded Stop: Enrollment
Phase 4	NCT00419471	May 2007 → Mar 2013	coronary artery disorder, depressive disorder	Chonnam National University Hospital	Completed	Met primary
Phase 4	NCT00767871	Mar → Aug 2007	panic disorder	Samsung Medical Center	Completed	No outcome recorded
Phase 4	NCT00442481	Feb 2007 → ?	major depressive disorder	Sheba Medical Center	Unknown	No outcome recorded
Phase 4	NCT03927950	Jan 2007 → Jan 2008	major depressive disorder	University of Tartu	Completed	No outcome recorded
Phase 4	NCT00708240	Jan 2007 → Aug 2010	obsessive-compulsive disorder	University of Ottawa	Unknown	No outcome recorded
Phase 4	NCT00902421	Jan 2007 → Jul 2009	overactive bladder	Samsung Medical Center	Completed	No outcome recorded
Phase 4	NCT00397059	Dec 2006 → Oct 2007	—	University of Southern Denmark	Completed	No outcome recorded
Phase 4	NCT00595699	Nov 2006 → Dec 2009	major depressive disorder, temporal lobe epilepsy	Conrad, Erich J., M.D.	Completed	No outcome recorded
Phase 4	NCT00352885	Oct 2006 → May 2010	depressive disorder	Emory University	Completed	No outcome recorded
Phase 4	NCT00384436	Oct 2006 → Oct 2007	major depressive disorder	Forest Laboratories	Completed	Missed primary
Phase 4	NCT00433121	Sep 2006 → Aug 2007	dementia	Innlandet Hospital Trust	Completed	No outcome recorded
Phase 4	NCT00574847	Sep 2006 → Nov 2011	myocardial ischemia	Duke University	Completed	Met primary
Phase 4	NCT00464711	Sep 2006 → Sep 2009	major depressive disorder	Massachusetts General Hospital	Completed	No outcome recorded
Phase 4	NCT00404755	Jul 2006 → Aug 2011	dysthymic disorder, major depressive disorder	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 4	NCT00456937	Jul 2006 → Sep 2008	schizophrenia	BeerYaakov Mental Health Center	Completed	No outcome recorded
Phase 4	NCT00130455	Apr 2006 → Jan 2008	depressive disorder	Psychiatric Hospital, Hillerod	Terminated	No outcome recorded
Phase 4	NCT00464191	Apr 2006 → Mar 2009	bipolar disorder	Nordfjord Psychiatric Centre	Terminated	No outcome recorded Stop: Enrollment
Phase 4	NCT00231335	Mar 2006 → Jul 2007	schizoaffective disorder, schizophrenia	Emory University	Completed	No outcome recorded
Phase 4	NCT00368862	Dec 2005 → Jun 2006	alcohol dependence, depressive disorder	Finnish Institute for Health and Welfare	Completed	No outcome recorded
Phase 4	NCT00209807	Sep 2005 → Jun 2009	major depressive disorder, pain agnosia	Hospital Universitari Vall d'Hebron Research Institute	Unknown	No outcome recorded
Phase 4	NCT00234312	Sep 2005 → Oct 2006	depressive disorder, dysthymic disorder	Oregon Health and Science University	Completed	No outcome recorded
Phase 4	NCT01148472	Sep 2005 → Sep 2006	major depressive disorder	H. Lundbeck A/S	Completed	Missed primary
Phase 4	NCT00296712	Feb 2005 → Jul 2006	dysthymic disorder, major depressive disorder	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 4	NCT00219349	Jan 2005 → Jul 2008	generalized anxiety disorder	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 4	NCT00229333	Dec 2004 → ?	depressive disorder	Sheba Medical Center	Unknown	No outcome recorded
Phase 4	NCT00296777	Dec 2004 → May 2007	dysthymic disorder, major depressive disorder	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 4	NCT00162968	Dec 2004 → Apr 2007	polyneuropathy	Odense University Hospital	Completed	No outcome recorded
Phase 4	NCT00105586	Dec 2004 → Jan 2008	generalized anxiety disorder	University of Pittsburgh	Completed	Met primary
Phase 4	NCT00151294	Nov 2004 → Oct 2006	depressive disorder, multiple sclerosis	Weill Medical College of Cornell University	Terminated	No outcome recorded
Phase 4	NCT00140257	Nov 2004 → Dec 2008	depressive disorder	Bispebjerg Hospital	Unknown	No outcome recorded
Phase 4	NCT00209170	May 2004 → May 2008	major depressive disorder, type 2 diabetes mellitus	Emory University	Completed	No outcome recorded
Phase 4	NCT00456430	Jul 2003 → Aug 2007	depressive disorder	Indiana University	Completed	No outcome recorded
Phase 4	NCT00183677	Jul 2003 → Jun 2009	depressive disorder	Massachusetts General Hospital	Completed	No outcome recorded
Phase 4	NCT00073697	May 2003 → Oct 2007	depressive disorder	University of Pittsburgh	Completed	No outcome recorded
Phase 4	NCT00157547	Apr 2003 → Aug 2006	major depressive disorder	Massachusetts General Hospital	Completed	No outcome recorded
Phase 4	NCT00260624	Feb 2003 → Dec 2006	Alzheimer disease	University of Rochester	Completed	No outcome recorded
Phase 4	NCT00812994	Jan 2003 → Dec 2006	depressive disorder	University of California, San Francisco	Completed	No outcome recorded
Phase 4	NCT00565422	Dec 2002 → Oct 2004	—	Icahn School of Medicine at Mount Sinai	Completed	No outcome recorded
Phase 4	NCT00918684	Dec 2002 → May 2010	depressive disorder	Weill Medical College of Cornell University	Completed	No outcome recorded
Phase 4	NCT00116532	Oct 2002 → Feb 2007	obsessive-compulsive disorder	Massachusetts General Hospital	Completed	No outcome recorded
Phase 4	NCT00115011	Sep 2002 → Nov 2005	impulse control disorder	Massachusetts General Hospital	Completed	No outcome recorded
Phase 4	NCT00220701	Jun 2002 → Nov 2008	dysthymic disorder	St. Luke's-Roosevelt Hospital Center	Completed	Missed primary
Phase 4	NCT00222820	Apr 2002 → Sep 2004	major depressive disorder	University of Pittsburgh	Completed	No outcome recorded
Phase 4	NCT00177216	Feb 2002 → May 2008	sleep disorder	University of Pittsburgh	Completed	No outcome recorded

Phase not applicable41 trials · 5 met primary · 3 missed
—	NCT07480525	Mar → Dec 2026 expected	major depressive disorder	Peking University	Not yet recruiting	No outcome recorded
—	NCT06001021	Aug → Sep 2023	mental disorder	Sameera Shafiq	Completed	Met primary
—	NCT05389046	Aug 2022 → Dec 2024	—	Peking University	Unknown	No outcome recorded
—	NCT05480150	Nov 2021 → Dec 2026 expected	bipolar disorder, major depressive disorder	First Affiliated Hospital of Zhejiang University	Recruiting	No outcome recorded
—	NCT03841474	Mar → Jun 2021	coronary artery disorder, depressive disorder	University Hospital Centre Zagreb	Unknown	No outcome recorded
—	NCT04478526	Apr 2020 → May 2021	generalized anxiety disorder	Dr. Nazanin Alavi	Completed	No outcome recorded
—	NCT07074652	Dec 2017 → Jun 2022	anxiety	UCLH/UCL Joint Research Office	Completed	No outcome recorded
—	NCT03148522	Jun 2017 → Dec 2021	—	Peking University	Unknown	No outcome recorded
—	NCT04013464	May 2016 → May 2018	major depressive disorder	Peking University Sixth Hospital	Completed	No outcome recorded
—	NCT02553161	Dec 2015 → Jul 2022	anxiety, bipolar disorder, depressive disorder	University of Cincinnati	Completed	No outcome recorded
—	NCT02516332	Dec 2015 → May 2020	anxiety, cardiovascular disorder	Duke University	Completed	Met primary
—	NCT03547219	Aug 2015 → Aug 2018	depressive disorder	Seoul National University	Completed	No outcome recorded
—	NCT02818751	May 2015 → May 2019	anxiety	University of Cincinnati	Completed	Met primary
—	NCT02285699	Nov 2014 → Mar 2016	obsessive-compulsive disorder	McMaster University	Completed	No outcome recorded
—	NCT02023567	Nov 2013 → Dec 2016	major depressive disorder	Peking University	Unknown	No outcome recorded
—	NCT02431845	Jan 2013 → Dec 2030 expected	obsessive-compulsive disorder	Severance Hospital	Recruiting	No outcome recorded
—	NCT01587326	Apr 2012 → Apr 2013	depressive disorder	Beitou Armed Forces Hospital, Taipei, Taiwan	Unknown	No outcome recorded
—	NCT01644071	Feb 2012 → Feb 2014	—	RWTH Aachen University	Completed	No outcome recorded
—	NCT00935246	Dec 2008 → Oct 2011	antidepressant type abuse, depressive disorder	Samsung Medical Center	Unknown	No outcome recorded
—	NCT00702780	Nov 2008 → Sep 2011	Alzheimer disease	Seoul National University Hospital	Completed	No outcome recorded
—	NCT00636649	Oct 2008 → Aug 2010	eating disorder	Duke University	Completed	No outcome recorded
—	NCT00736021	Sep 2008 → Mar 2010	post-traumatic stress disorder	Hadassah Medical Organization	Completed	No outcome recorded
—	NCT00703742	Jun 2008 → Jun 2011	depressive disorder	Kunming Medical University	Completed	No outcome recorded
—	NCT01214044	May 2008 → Dec 2011	depressive disorder	Oregon Health and Science University	Completed	Missed primary
—	NCT01527474	Apr 2008 → May 2009	postpartum depression	BC Women's Hospital & Health Centre	Completed	No outcome recorded
—	NCT00613067	Dec 2007 → Apr 2010	generalized anxiety disorder	Inje University	Completed	No outcome recorded
—	NCT00550485	Oct 2007 → Jul 2018	—	Max-Planck-Institute of Psychiatry	Completed	No outcome recorded
—	NCT00601965	Oct 2007 → Sep 2011	generalized anxiety disorder	Veterans Medical Research Foundation	Completed	Met primary
—	NCT00754936	May 2007 → May 2015	depressive disorder	Weill Medical College of Cornell University	Completed	No outcome recorded
—	NCT00456014	Sep 2006 → May 2012	major depressive disorder	New York State Psychiatric Institute	Completed	No outcome recorded
—	NCT00367341	Aug 2006 → Aug 2011	major depressive disorder	Emory University	Completed	No outcome recorded
—	NCT00643162	Jun 2006 → Feb 2010	major depressive disorder	Cedars-Sinai Medical Center	Terminated	Missed primary Stop: Enrollment
—	NCT00232700	Sep 2005 → Dec 2008	major depressive disorder	Charite University, Berlin, Germany	Completed	No outcome recorded
—	NCT00220480	Feb 2005 → Jun 2011	major depressive disorder	Sheba Medical Center	Unknown	No outcome recorded
—	NCT00146900	Aug 2004 → Jan 2008	post-traumatic stress disorder	Hadassah Medical Organization	Completed	Missed primary
—	NCT00277108	Feb 2004 → Apr 2007	postpartum depression	University of Rochester	Completed	No outcome recorded
—	NCT00194948	Sep 2003 → Apr 2007	major depressive disorder	Weill Medical College of Cornell University	Completed	No outcome recorded
—	NCT01024140	Feb 2003 → Dec 2004	post-traumatic stress disorder	Northern California Institute of Research and Education	Completed	No outcome recorded
—	NCT00071643	Sep 2002 → Nov 2008	depressive disorder, stroke disorder	Robert G. Robinson	Completed	Met primary
—	NCT00749125	Jul 2001 → Jan 2008	depressive disorder	Washington University School of Medicine	Completed	No outcome recorded
—	NCT00255554	—	borderline personality disorder	Bronx VA Medical Center	Unknown	No outcome recorded

Comparator or background therapy204 trials
Phase 0	NCT03887624 Background	May 2019 → Apr 2021	major depressive disorder	Zhejiang University	Completed	No outcome recorded
Phase 1	NCT06965569 Background	Apr → Dec 2025	—	Alar Pharmaceuticals Inc.	Completed	No outcome recorded
Phase 1	NCT06476509 Comparator	May 2024 → Jan 2025	major depressive disorder	Vigonvita Life Sciences	Completed	No outcome recorded
Phase 1	NCT03912974 Comparator	Jul 2019 → Nov 2020	—	University Hospital, Basel, Switzerland	Completed	No outcome recorded
Phase 1	NCT02072278 Comparator	Feb → Nov 2014	—	H. Lundbeck A/S	Completed	No outcome recorded
Show all 204 trials opens the full record — a long page

News releases announcing trial results or a regulatory action · 10

Date	Issuer	Release
2014-11-28	Mochida Pharmaceutical Company, Ltd.	Regulatory 抗うつ剤「レクサプロ(R)錠10mg」の日本での効能・効果追加申請のお知らせ mochida.co.jp ↗
2014-06-18	Takeda	Results Results of a New Study of Brintellix ® (vortioxetine) vs. Escitalopram on Sexual Functioning in Well Treated MDD Patients Experiencing Treatment-Emergent Sexual Dysfunction takeda.com ↗ Takeda and Lundbeck Announce Results at American Society of Clinical Psychopharmacology Annual Meeting Hollywood, Fla. U.S.A., June 17, 2014 and Osaka, Japan, June 18, 2014 —Takeda Pharmaceutical Company Limited (Takeda) and H. Lundbeck A/S (Lundbeck) announced that the companies presented results about sexual functioning from a head-to-head study of Brintellix ® (vortioxetine) vs. escitalopram in patients with well treated major depressive disorder (MDD) experiencing treatment-emergent sexual dysfunction (TESD).
2013-10-01	Bristol-Myers Squibb	Results Bristol-Myers Squibb to Present Range of New Hepatitis C Data at the 2013 American Association for the Study of Liver Diseases (AASLD) Annual Meeting bms.com ↗ No Clinically-Relevant Interactions Between Asunaprevir and Selective Serotonin Reuptake Inhibitors (Escitalopram and Sertraline) in Healthy Subjects
2011-07-21	Tanabe Pharma Corporation	Regulatory The NHI Drug Price Listing and Launch of an Anti-depressant, Lexapro® 10mg tanabe-pharma.com ↗ today announced that Lexapro® 10mg (generic name: escitalopram), for which Mochida obtained the marketing approval, will be launched on August 22, 2011 following the NHI (National Health Insurance) Drug Price was listed.
2011-07-21	Mochida Pharmaceutical Company, Ltd.	Regulatory 抗うつ剤「レクサプロ(R)錠10mg」の薬価基準収載ならびに新発売のお知らせ mochida.co.jp ↗
2011-04-22	Mochida Pharmaceutical Company, Ltd.	Regulatory 抗うつ剤「レクサプロ(R)錠10mg」の製造販売承認取得のお知らせ mochida.co.jp ↗
2010-09-15	Mochida Pharmaceutical Company, Ltd.	Regulatory 抗うつ剤「エスシタロプラム」の国内での製造販売承認申請のお知らせ mochida.co.jp ↗
2006-05-22	Teva Branded Pharmaceutical Products R&D, Inc.	Regulatory Teva Announces Approval of Generic Lexapro® Tablets tevapharm.com ↗
2006-05-22	Eli Lilly and Company	Results New Data Presented on the Effect of Cymbalta(R) on Sexual Function in Depressed Patients lilly.com ↗
2005-12-13	Eli Lilly and Company	Results New Study Suggests Cymbalta(R) Reduced Depression Symptoms At Least As Fast As a Leading Competitor lilly.com ↗ Cymbalta(R) (duloxetine hydrochloride) reduced symptoms of depression at least as fast as Lexapro(R) (escitalopram) by the end of two weeks, according to results from the first head-to-head study comparing the two antidepressants.

All press releases naming this drug 14 releases

Date	Issuer	Release
2014-11-28	Mochida Pharmaceutical Company, Ltd.	抗うつ剤「レクサプロ(R)錠10mg」の日本での効能・効果追加申請のお知らせ mochida.co.jp ↗
2014-06-18	Takeda	Results of a New Study of Brintellix ® (vortioxetine) vs. Escitalopram on Sexual Functioning in Well Treated MDD Patients Experiencing Treatment-Emergent Sexual Dysfunction takeda.com ↗
2013-10-01	Bristol-Myers Squibb	Bristol-Myers Squibb to Present Range of New Hepatitis C Data at the 2013 American Association for the Study of Liver Diseases (AASLD) Annual Meeting bms.com ↗
2012-03-14	Teva Branded Pharmaceutical Products R&D, Inc.	Teva Announces Launch of Generic Lexapro® in the United States; Awarded 180-Day Period of Marketing Exclusivity tevapharm.com ↗
2011-10-19	Almirall, S.A.	Almirall and Lundbeck announce a co-promotion agreement for escitalopram in Italy almirall.com ↗
2011-07-21	Tanabe Pharma Corporation	The NHI Drug Price Listing and Launch of an Anti-depressant, Lexapro® 10mg tanabe-pharma.com ↗
2011-07-21	Mochida Pharmaceutical Company, Ltd.	抗うつ剤「レクサプロ(R)錠10mg」の薬価基準収載ならびに新発売のお知らせ mochida.co.jp ↗
2011-04-22	Mochida Pharmaceutical Company, Ltd.	抗うつ剤「レクサプロ(R)錠10mg」の製造販売承認取得のお知らせ mochida.co.jp ↗
2010-09-15	Mochida Pharmaceutical Company, Ltd.	抗うつ剤「エスシタロプラム」の国内での製造販売承認申請のお知らせ mochida.co.jp ↗
2010-01-07	Tanabe Pharma Corporation	Conclusion of Co-marketing Agreement for an Anti-Depressant, Escitalopram in Japan tanabe-pharma.com ↗
2009-07-10	Sun Pharmaceutical Industries, Inc.	Sun Pharma to license key Escitalopram® patent applications to Lundbeck® sunpharma.com ↗
2006-05-22	Teva Branded Pharmaceutical Products R&D, Inc.	Teva Announces Approval of Generic Lexapro® Tablets tevapharm.com ↗
2006-05-22	Eli Lilly and Company	New Data Presented on the Effect of Cymbalta(R) on Sexual Function in Depressed Patients lilly.com ↗
2005-12-13	Eli Lilly and Company	New Study Suggests Cymbalta(R) Reduced Depression Symptoms At Least As Fast As a Leading Competitor lilly.com ↗

Evidence & citations 18 cited values

Every value below carries the sentence it was read from. 453 sources stand behind the page.

Field	Value	Cited text
Known as	escitalopram	“The proposed study will consist of a double-blinded, randomized controlled trial using a crossover design to assess the effects of SSRIs (escitalopram oxalate, Lexapro®, Forest...” NCT01788969 ↗ 434 “we have restricted the IMPACT list of antidepressants to SSRIs (sertraline, escitalopram, paroxetine, fluoxetine, citalopram), duloxetine, bupropion, and mirtazapine. These...” NCT02458690 ↗ “Participants receive only clinical routine antidepressant treatment,Which include fluoxetine (Prozac); sertraline (Zoloft); paroxetine (Paxil); citalopram (Celexa)...” NCT01831440 ↗ “Antidepressant medications may include the following: citalopram (Celexa), escitalopram (Lexapro), paroxetine (Paxil CR), sertraline (Zoloft), venlafaxine XR (Effexor XR),...” NCT00564278 ↗ “Medication group is a control group that can choose to use the serotonin reuptake inhibitors (SSRIs) approved by China food and Drug Administration (SFDA) for the treatment of...” NCT03558256 ↗ “In cases of intolerance or adverse reaction to fluoxetine, the investigator will switch to sertraline (25 to 200mg) or escitalopram (5 to 20mg), the other two antidepressants...” NCT05002309 ↗ “ADT such as citalopram, escitalopram, fluoxetine, sertraline, paroxetine, vilazodone, venlafaxine, desvenlafaxine, duloxetine or bupropion prescribed in accordance with its...” NCT01838876 ↗ “Eligible adults (18-65 years) were assigned to antidepressant monotherapy (escitalopram or venlafaxine extended-release) plus lisdexamfetamine dimesylate-matching placebo...” PMID 28857719 ↗ Aug 2017 “SSRI (paxil CR, es-citalopram, fluoxetine, sertraline) start with (paxil CR 12.5mg, es-citalopram 10mg, fluoxetine 20mg, sertraline 50mg) for 1 week up to maximal dosage,...” NCT01357967 ↗ “Drug: Antidepressant (citalopram, duloxetine, escitalopram, sertraline, or venlafaxine XR) + cariprazine (0.1-0.3 mg/d) Oral, once daily for 8 weeks following an 8 week...” NCT00854100 ↗ “SPD489 20mg, 30mg, 50mg, or 70mg + Antidepressant (either escitalopram oxalate, sertraline hydrochloride, venlafaxine hydrochloride extended release or duloxetine...” NCT01436175 ↗ Show 424 more sources
Known as	cipralex	“The aim of this study is to evaluate the therapeutic effect of escitalopram (cipralex) in the treatment of negative symptoms in schizophrenic patients receiving either typical...” NCT00148447 ↗ 7 “The purpose of the study is to evaluate tolerability and efficacy of escitalopram (Cipralex) treatment in doses beyond 20mg (20-40 mg/d) in patients with OCD and schizophrenia,...” NCT00708396 ↗ “Cipralex (escitalopram)” NCT00368862 ↗ “Cipralex (escitalopram)” NCT06675851 ↗ NCT01293838 ↗ NCT01644071 ↗ NCT01961180 ↗ NCT00485888 ↗
Known as	ESC	“BACKGROUND: In this study, the impact of quetiapine fumarate extended release (QXR) and escitalopram (ESC) on HPA axis activity was investigated in depressed patients in...” PMID 24275013 ↗ Oct 2013 5 “In our experience, venlafaxine (VLX) and escitalopram (ESC) are the two antidepressants best tolerated and least likely to interfere with oncotherapy for patients with MDD and...” NCT04973930 ↗ “escitalopram (ESC) added a second phase using a synchronous, videoconference (VC) format” PMID 40324655 ↗ May 2025 “initially treated with a combination of escitalopram (ESC) plus bupropion (BUP)” PMID 19820552 ↗ Sep 2009 “plus escitalopram (ESC) 20 mg once daily for six weeks” PMID 34545997 ↗ Sep 2021 “in combination with escitalopram (ESC).” PMID 31630035 ↗ Oct 2019
Known as	escitalopram (Lexapro)	“escitalopram (Lexapro)” NCT01460212 ↗ 3 “escitalopram = Lexapro” NCT00296712 ↗ “Escitalopram (Lexapro)” NCT00610506 ↗ “Escitalopram, Lexapro” NCT01916824 ↗
Known as	Escitalopram 20 mg (Lexapro, Tablet)	“Escitalopram 20 mg (Lexapro, Tablet)” NCT01871701 ↗
Known as	Escitalopram = Cipralex/Lexapro/Seroplex/Sipralexa	“Escitalopram = Cipralex/Lexapro/Seroplex/Sipralexa” NCT00807248 ↗
Known as	escitalopram oxalate	“The proposed study will consist of a double-blinded, randomized controlled trial using a crossover design to assess the effects of SSRIs (escitalopram oxalate, Lexapro®, Forest...” NCT01788969 ↗ 10 “For women, a pregnancy test will also be administered no more than 48 hours before SPECT-CT imaging and the beginning of escitalopram oxalate (Lexapro) treatment.” NCT01401595 ↗ “Escitalopram oxalate (antidepressant) 20 mg/day oral + 20, 30, or 50 mg SPD489 oral once daily for 6 weeks” NCT00905424 ↗ “Escitalopram oxalate (Reconter), 10mg/day (first 3 weeks) and 20mg/day (week 3 to week 10).” NCT01894815 ↗ “escitalopram oxalate , a selective-5HT reuptake inhibitor (SSRI)” NCT01538693 ↗ “in Depressed Patients on Escitalopram Oxalate (Lexapro)” NCT00416221 ↗ “Escitalopram (as escitalopram oxalate) tablet” NCT07645807 ↗ “Escitalopram Oxalate Tablets 20 mg” NCT00648661 ↗ “Escitalopram oxalate tablets” NCT06680531 ↗ “Drug: Escitalopram Oxalate” NCT05004987 ↗ NCT05737511 ↗
Known as	escitalopram/Cipralex	“escitalopram/Cipralex” NCT01219686 ↗
Known as	Innovator Escitalopram	“fixed dose(generic escitalopram 10mg/d or Innovator Escitalopram(Lexapro®) 10mg/d)” NCT00866593 ↗
Known as	Lexapro	“The proposed study will consist of a double-blinded, randomized controlled trial using a crossover design to assess the effects of SSRIs (escitalopram oxalate, Lexapro®, Forest...” NCT01788969 ↗ 29 “Participants receive only clinical routine antidepressant treatment,Which include fluoxetine (Prozac); sertraline (Zoloft); paroxetine (Paxil); citalopram (Celexa)...” NCT01831440 ↗ “Antidepressant medications may include the following: citalopram (Celexa), escitalopram (Lexapro), paroxetine (Paxil CR), sertraline (Zoloft), venlafaxine XR (Effexor XR),...” NCT00564278 ↗ “The goal of this clinical trial is to evaluate the acute effects of escitalopram (Lexapro®) on select brain networks during task-based functional magnetic resonance imaging...” NCT06826326 ↗ “The purpose of the study is to evaluate the efficacy and safety of flexible doses of escitalopram (Lexapro) compared to sertraline (Zoloft) for treatment of Dysthymic Disorder.” NCT00234312 ↗ “Throughout the study, all subjects will receive either escitalopram (Lexapro) or citalopram (Celexa) on the basis of the study doctor's clinical judgment.” NCT00361218 ↗ “This study compares the effectiveness of the combination of antidepressants: Lexapro and Pramipexole, with the effectiveness of each antidepressant alone.” NCT00086307 ↗ “The investigators will use the SSRI escitalopram (Lexapro), which has received FDA approval for the treatment of anxiety, in 5 mg capsules.” NCT02516332 ↗ “Escitalopram (Lexapro) 5mg daily for first 2 weeks, and then 10 mg daily for 8 weeks versus Placebo for 10 weeks” NCT02153567 ↗ “the SSRI escitalopram (Lexapro), with the most recently available SNRI, duloxetine” NCT00215228 ↗ “Venlafaxine (Effexor), Duloxetine (Cymbalta), Escitalopram (Lexapro)” NCT00200902 ↗ Show 19 more sources
Known as	Lexapro (escitalopram)	“Lexapro (escitalopram)” NCT00754793 ↗ 1 “Lexapro (escitalopram)” NCT00642694 ↗
Known as	Reconter	“Escitalopram oxalate (Reconter), 10mg/day (first 3 weeks) and 20mg/day (week 3 to week 10).” NCT01894815 ↗
Known as	s-CIT	“To define these subtypes, a prospectively-treated cohort of 100 patients will be randomized to receive either escitalopram (s-CIT) or CBT for the first 12 weeks, with...” NCT00367341 ↗ 2 “Subjects will be randomized to receive either escitalopram (s-CIT) or CBT for 12 weeks.” NCT02137369 ↗ “Escitalopram (SCIT) is frequently prescribed to breastfeeding women.” PMID 32162723 ↗ Apr 2020
Known as	S-citalopram	“effect of an antidepressive pre-treatment over two weeks and a continuously concomitant treatment with Escitalopram (S-citalopram) on frequency and severity of depression” NCT00136318 ↗ 1 NCT00655057 ↗
Action	Inhibit	“a selective serotonin reuptake inhibitor” NCT00070941 ↗
Modality	Small molecule	“Escitalopram (an SSRI-compound)” NCT00971815 ↗
Route	Oral	“40 subjects receiving oral escitalopram 20mg or 40 mg daily, in two divided doses, and placebo SAM-e.” NCT00070941 ↗
Target	CYP2D6	“It is stated that escitalopram is only a weak inhibitor of CYP2D6” NCT00692263 ↗