Analgesic Effect of Escitalopram in Total Knee Arthroplasty (TKA)

Phase 4 Completed 120 enrolled Hvidovre University Hospital Lundbeck Foundation · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Pain is a major problem after TKA, especially in patients with high pain catastrophizing. Newer MR-scan studies indicate that Escitalopram may have an immediate cognitive and emotional effect. The investigators therefore investigate the effect of Escitalopram as a perioperative analgesic.

Timeline

Start: 2011-09
Primary completion: 2013-04
Completion: 2013-05

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Escitalopram	Small molecule	10 mg	—

Indications

No indication recorded.