drugset / Trial / NCT01477203

Multimodal Assessment of Neurobiological Markers for Psychiatric Disorders

NCT01477203

Phase 4 Completed 289 enrolled Medical University of Vienna
Non-randomizedParallel-groupOpen-labelDiagnostic

Summary

MAN-BIOPSY pursues the concrete research question whether novel biological and psycho-physiological clusters or categories can be defined to improve treatment and minimize side effects in psychiatry, based on a synopsis of physiological, behavioural, genetic and endocrinological parameters. One major aspect of our research approach is its focuses on the identification of dysfunctions in fundamental information processing mechanisms and neurocomputational mechanisms, and is not restricted to symptom-oriented tasks. The main objectives of MAN-BIOPSY are therefore * to identify biological and psycho-physiological parameters for major depressive disorders and anxiety disorders, and * to identify predictive markers for treatment response and type/severity of side effects for these disorders.

Timeline

Start
2011-11
Primary completion
2016-09
Completion
2016-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator Escitalopram Small molecule 5 mg
Comparator Escitalopram Small molecule 10 mg
Comparator Escitalopram Small molecule 20 mg