drugset / Trial / NCT06692361
Assessment of the Efficacy and Safety of Fecal Microbiota Transplantation (FMT) in Patients With Major Depressive Disorder
Recruiting
214 enrolled
Gang Wang
First Affiliated Hospital of Zhejiang University · collabShandong Daizhuang Hospital · collabThe First Hospital of Hebei Medical University · collabTianjin Anding Hospital · collabWest China Hospital · collabWuhu Fourth People's Hospital · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
This study aimed to evaluate the efficacy and safety of fecal microbiota transplantation (FMT) in patients with major depressive disorder (MDD) who exhibit suboptimal early response to antidepressant treatment. Additionally, it sought to investigate the impact of FMT on biological indicators, including intestinal microbiota and metabolites, in individuals with MDD
Timeline
- Start
- 2025-01-01
- Primary completion
- 2026-06
- Completion
- 2026-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | FMT | Unknown | 1 g | Oral |
| Background | Escitalopram | Small molecule | — | — |